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Pre-mRNA Interference of VEGF Pathways in Ocular Angiogenesis

Pre-mRNA Interference of VEGF Pathways in Ocular Angiogenesis
眼部血管生成中 VEGF 通路的前 mRNA 干扰
批准号：
7919381
负责人：
BALAMURALI K AMBATI
金额：
$0.0万
依托单位：
VA SALT LAKE CITY HEALTHCARE SYSTEM
依托单位国家：
美国
项目类别：
财政年份：
2009
资助国家：
美国
项目状态：
已结题
起止时间：
2009-10-01 至 2013-09-30
来源：
https://reporter.nih.gov/project-details/7919381
关键词：
AffectAge related macular degenerationAlbuminsAlternative SplicingBindingBlindnessBlood VesselsBruch&aposs basal membrane structureCCL2 geneCellsChoroidChoroidal NeovascularizationClinicalCodeComplicationCorneaCorneal InjuryCorneal NeovascularizationCustomDevelopmentDevicesDiabetes MellitusDiabetic RetinopathyElementsEventExonsExudative age-related macular degenerationEyeEye InjuriesEye PartFluoresceinGenesGeneticGraft RejectionHealthHomingInjuryIntegrin alphaVbeta3IntronsKeratoplastyLabelLasersLengthMacular degenerationMalignant NeoplasmsMasksMembraneMessenger RNAModelingMusOligonucleotidesOligopeptidesOutcomePathway interactionsPatientsPlasmidsPosterior eyeball segment structureProtein IsoformsRGD (sequence)RNA SplicingRegulationRehabilitation therapyResearchRetinaRetinal NeovascularizationSilicon DioxideSisterSoldierSpliceosomesStructureSystemTechniquesTechnologyTestingTissuesTranscendTranslatingTraumaVascular Endothelial Growth Factor ReceptorVascular Endothelial Growth Factor Receptor-1Vascular Endothelial Growth Factor Receptor-2Vascular Endothelial Growth FactorsVeteransVisionVisual impairmentWild Type Mousebasecancer therapycombatfightingimprovedmRNA Precursormaculananoparticleneovascularnovelnovel strategiesnovel therapeutic interventionocular angiogenesispreventpublic health relevancereceptorreceptor expressionrestorationretinal angiogenesisretinal damagesmall molecule

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