Pre-mRNA Interference of VEGF Pathways in Ocular Angiogenesis

眼部血管生成中 VEGF 通路的前 mRNA 干扰

• 批准号: 7919381
• 负责人: BALAMURALI K AMBATI
• 金额: --
• 依托单位: VA SALT LAKE CITY HEALTHCARE SYSTEM
• 依托单位国家: 美国
• 财政年份: 2009
• 资助国家: 美国
• 起止时间: 2009-10-01 至 2013-09-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7919381
• 关键词: Affect; Age related macular degeneration; Albumins; Alternative Splicing; Binding; Blindness; Blood Vessels; Bruch' s basal membrane structure; CCL2 gene; Cells; Choroid; Choroidal Neovascularization; Clinical; Code; Complication; Cornea; Corneal Injury; Corneal Neovascularization; Custom; Development; Devices; Diabetes Mellitus; Diabetic Retinopathy; Elements; Event; Exons; Exudative age-related macular degeneration; Eye; Eye Injuries; Eye Part; Fluorescein; Genes; Genetic; Graft Rejection; Health; Homing; Injury; Integrin alphaVbeta3; Introns; Keratoplasty; Label; Lasers; Length; Macular degeneration; Malignant Neoplasms; Masks; Membrane; Messenger RNA; Modeling; Mus; Oligonucleotides; Oligopeptides; Outcome; Pathway interactions; Patients; Plasmids; Posterior eyeball segment structure; Protein Isoforms; RGD (sequence); RNA Splicing; Regulation; Rehabilitation therapy; Research; Retina; Retinal Neovascularization; Silicon Dioxide; Sister; Soldier; Spliceosomes; Structure; System; Techniques; Technology; Testing; Tissues; Transcend; Translating; Trauma; Vascular Endothelial Growth Factor Receptor; Vascular Endothelial Growth Factor Receptor-1; Vascular Endothelial Growth Factor Receptor-2; Vascular Endothelial Growth Factors; Veterans; Vision; Visual impairment; Wild Type Mouse; base; cancer therapy; combat; fighting; improved; mRNA Precursor; macula; nanoparticle; neovascular; novel; novel strategies; novel therapeutic intervention; ocular angiogenesis; prevent; public health relevance; receptor; receptor expression; restoration; retinal angiogenesis; retinal damage; small molecule