2015 RNA Nanotechnology Gordon Research Conference

2015年RNA纳米技术戈登研究会议

• 批准号: 8831228
• 负责人: PEIXUAN GUO
• 金额: $ 2.5万
• 依托单位: GORDON RESEARCH CONFERENCES
• 依托单位国家: 美国
• 财政年份: 2015
• 资助国家: 美国
• 起止时间: 2015-01-15 至 2016-01-14
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8831228
• 关键词: Academia; Address; Advertising; Amaze; Antibodies; Area; Attention; Base Pairing; Basic Science; Binding; Biochemical; Biochemistry; Biocompatible Materials; Bioinformatics; Biological Markers; Biological Sciences; Biophysics; Cancer Biology; Cellular biology; Chemicals; Chemistry; Clinical Investigator; Code; Collaborations; Communities; Construction Materials; DNA; Development; Discipline; Disease; Disease Pathway; Disease Progression; Drug Industry; Drug Targeting; Early Diagnosis; Engineering; Eye diseases; Fostering; Free Energy; Funding; Future; Genome; Goals; Government; Growth; Health; Human Genome; Imaging technology; Immunology; Individual; Junk DNA; Knowledge; Malignant Neoplasms; Microbiology; Modality; Modeling; Monitor; Nanostructures; Nanotechnology; Nature; Pharmaceutical Preparations; Pharmacologic Substance; Postdoctoral Fellow; Principal Investigator; Private Sector; Property; Proteins; Public Sector; RNA; RNA Computations; RNA Folding; RNA Processing; Rare Diseases; Reporting; Research; Research Personnel; Schedule; Science; Scientist; Staging; Structure; Technology; Therapeutic; Translating; Translational Research; Untranslated RNA; Virus Diseases; Woman; Work; base; career; clinical application; design; disease diagnosis; extracellular; flexibility; fundamental research; graduate student; image guided; improved; in vivo; meetings; nanomedicine; nanoparticle; nanosensors; nanotherapeutic; non-invasive imaging; novel; programs; public health relevance; research clinical testing; single molecule; stoichiometry; structural biology; symposium; therapeutic development; undergraduate student

 DESCRIPTION (provided by applicant): The goal of this R13 application is to request partial funding support for the upcoming Gordon Research Conference (GRC) on RNA Nanotechnology, scheduled to be held Feb 1-6, 2015 in Ventura, CA. This meeting will be chaired by Peixuan Guo, who pioneered the field of RNA Nanotechnology. Neocles Leontis with extensive expertise in RNA structure and RNA bioinformatics will serve as the vice-chair. Over the last five years, RNA nanotechnology has attracted widespread attention and has become a vigorous and rapidly emerging new field of science (Guo P. Nature Nanotechnology, 2010, 5:833). RNA nanotechnology exploits the modularity and designability of RNA folding and assembly at multiple structural levels to rationally design and functionalize RNA nanoparticles for diverse applications in nanotechnology and nanomedicine. This GRC is geared towards the applications of RNA nanoparticles for early disease diagnosis; non-invasive imaging to monitor the progression of diseases; and targeting and treatment of a wide range of diseases from cancer, bacterial, viral infections to rare eye diseases. The specific aim of this conference is t provide a forum for advancing this new field from discovery to clinical evaluations. Accordingly, researchers from public and private sectors will be invited to: (1) share existing knowledge and set future research initiatives in the field; and (2) foster collaborations between physical/engineering scientists with life sciences researchers, and basic science researchers with clinical investigators. The meeting will cover a range of topics, including biophysical and single molecule approaches for characterization of RNA nanostructures; structural and functional studies on RNA nanoparticles by chemical or biochemical approaches; computation, prediction, and modeling of RNA nanoparticle structures focusing on inter-molecular interactions; application of RNA nanoparticles in therapeutics for the treatment of diseases; and finally two sessions covering the exciting new area of extracellular RNA for biomarker and therapeutic development. The invited speakers and discussion leaders for this GRC will include a mix of world-renowned researchers in the field as well as exceptional junior-level investigators from around the world. The meeting will be advertised to a diverse audience to include early career (undergraduate/graduate students and postdocs) and under-represented scientists in the field.

 描述（由申请人提供）：此R13申请的目标是为即将举行的戈登研究会议（GRC）RNA纳米技术申请部分资金支持，计划于2015年2月1日至6日在加利福尼亚州文图拉举行。本次会议将由RNA纳米技术领域的先驱郭培轩主持。在RNA结构和RNA生物信息学方面拥有丰富专业知识的Neocles Leontis将担任副主席。在过去的五年里，RNA纳米技术引起了广泛的关注，并已成为一个充满活力和迅速崛起的新的科学领域（郭P. Nature Nanotechnology，2010，5：833）。RNA纳米技术利用RNA折叠和组装在多个结构水平上的模块性和可设计性，以合理设计和功能化RNA纳米颗粒，用于纳米技术和纳米医学的各种应用。该GRC面向RNA纳米颗粒在早期疾病诊断中的应用;非侵入性成像以监测疾病进展;以及靶向和治疗从癌症，细菌，病毒感染到罕见眼病的各种疾病。 本次会议的具体目标是提供一个论坛，推动这一新领域从发现到临床评价。因此，来自公共和私营部门的研究人员将被邀请：（1）分享现有知识，并制定该领域未来的研究计划;（2）促进物理/工程科学家与生命科学研究人员，基础科学研究人员与临床研究人员之间的合作。会议将讨论多个课题，包括RNA纳米结构的生物物理和单分子表征方法; RNA纳米颗粒的结构和功能的化学或生物化学研究; RNA纳米颗粒结构的计算、预测和建模，重点是分子间的相互作用; RNA纳米颗粒在疾病治疗中的应用; RNA纳米颗粒在生物医学中的应用。最后两个会议涵盖了令人兴奋的新领域的细胞外RNA的生物标志物和治疗的发展。 本次GRC的特邀演讲者和讨论领导者将包括该领域的世界知名研究人员以及来自世界各地的优秀初级研究人员。会议将向不同的受众做广告，包括早期职业（本科生/研究生和博士后）和该领域代表性不足的科学家。