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Malaria Drug Resistance and Disease Virulence

Malaria Drug Resistance and Disease Virulence
疟疾耐药性和疾病毒力
批准号：
8156841
负责人：
Thomas E Wellems
金额：
$87.48万
依托单位：
NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES
依托单位国家：
美国
项目类别：
财政年份：
--
资助国家：
美国
项目状态：
未结题
起止时间：
至
来源：
https://reporter.nih.gov/project-details/8156841
关键词：
DiseaseDrug resistanceMalariaVirulence

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中文摘要
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英文摘要
Our research project focuses on how malaria parasites become resistant to major antimalarial drugs and why strains of the most deadly malaria parasite (Plasmodium falciparum) show different infectivities to cells of humans and certain other primates. In each of these areas we seek research advances that can improve the knowledge of disease processes in malaria and thereby support the development or testing of new antimalarial chemotherapies, diagnostic tools, and vaccines. The research activities in our program are multidisciplinary and include field studies in malarious regions as well as programs of basic laboratory investigation.
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Malaria Pathogenesis and Clinical Immunity
Malaria Drug Resistance and Disease Virulence
Biochemical And Biophysical Parasitology
Dry Season Ecology of Malaria Vectors
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