课题基金 / 基金详情

Malaria Drug Resistance and Disease Virulence

Malaria Drug Resistance and Disease Virulence
疟疾耐药性和疾病毒力
批准号：
8745299
负责人：
Thomas E Wellems
金额：
$134.93万
依托单位：
NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES
依托单位国家：
美国
项目类别：
财政年份：
--
资助国家：
美国
项目状态：
未结题
起止时间：
至
来源：
https://reporter.nih.gov/project-details/8745299
关键词：
AfricaAntimalarialsAreaAsiaCessation of lifeDevelopmentDiagnosticDiagnostic testsDiseaseDrug resistanceGenesHumanInfectionInvestigationKnowledgeLaboratoriesMalariaModelingParasitesPlasmodium falciparumPlasmodium vivaxPrimatesProcessResearchResearch ActivityResearch Project GrantsResistanceSouth AmericaTestingVaccinesVirulencechemotherapydisabilitydrug candidatefield studyimprovedmultidisciplinarynovel diagnosticsnovel therapeutic interventionprogramsresponsetoolvaccine candidate

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中文摘要
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英文摘要
Our research project focuses on how malaria parasites become resistant to major antimalarial drugs and why strains of the two species responsible most human malaria disability and death (Plasmodium falciparum and Plasmodium vivax) show different infectivities to humans and other primates. In these areas of research, we seek advances that can improve the knowledge of disease processes in malaria and thereby support the development or testing of new antimalarial chemotherapies, diagnostic tools, and vaccines. The research activities in our program are multidisciplinary and include field studies in malarious regions of Africa, Asia and South America, as well as programs of basic laboratory investigation.
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Malaria Pathogenesis and Clinical Immunity
Malaria Drug Resistance and Disease Virulence
Biochemical And Biophysical Parasitology
Dry Season Ecology of Malaria Vectors
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