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Study the role(s) of p53 in embryonic stem cells

Study the role(s) of p53 in embryonic stem cells
研究 p53 在胚胎干细胞中的作用
批准号:
8157662
负责人:
Jing Huang
金额:
$39.77万
依托单位国家:
美国
项目类别:
财政年份:
--
资助国家:
美国
项目状态:
未结题
起止时间:

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中文摘要
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英文摘要
During fiscal year of 2009, we used ChIP-chip and gene expression microarray approaches to examine the role of p53 in embryonic stem cells. We surprisingly found that p53 regulates the Wnt sginaling pathway in embryonic stem cells. The Wnt signaling pathway plays important role in development and tumorigenesis. The underlying mechanism is currently under investigation in the lab. In the future, we plan to use in vivo mouse model to test our hypothesis that p53 has dual functions in embryonic stem cells.
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  • 批准号:
    10696114
  • 项目类别:
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  • 财政年份:
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  • 负责人:
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Characterizing Disease Trajectory for Improving Treatment in Pediatric Crohn's Disease
  • 批准号:
    10414884
  • 项目类别:
  • 资助金额:
    $61.68万
  • 财政年份:
    2019
  • 负责人:
    Jing Huang
  • 依托单位:
Characterizing Disease Trajectory for Improving Treatment in Pediatric Crohn's Disease
  • 批准号:
    10641954
  • 项目类别:
  • 资助金额:
    $61.68万
  • 财政年份:
    2019
  • 负责人:
    Jing Huang
  • 依托单位:
海外基金