Biopolymers & Proteomics

生物聚合物和蛋白质组学核心是一个共享资源，为科赫研究所成员提供 各种基本服务，能够合成和分析生物材料，并需要 先进的技术专业知识和最先进的仪器设备。在当前时期，这一任务是 作为更大规模重组计划的一部分，CORE进行了修改。首先，所有与DNA相关的活动都被外包或 转移到科赫研究所基因组核心，从而使生物聚合物和蛋白质组学核心专业化 在蛋白质、蛋白质组学和质谱学服务方面。其次，这些能力得到了扩展， 通过以下方式得到加强：搬进一个更大的、定制设计的空间；购置大量新仪器； 以及聘请一名提供定制技术支持的专家质谱学顾问 和/或高端蛋白质组学项目的培训。重要的是，超过80%的中心都在使用核心 成员，包括所有四个项目的调查人员。因此，这种共享资源对于 科赫研究所任务的成功。在接下来的一段时间里，这个核心将继续提供广泛的 最先进的技术支持中心成员的研究计划。值得注意的是，请求的 CCSG 44年的预算仅为39年所要求和建议预算的三分之二。

The Biopolymers & Proteomics Core is a Shared Resource that provides Koch Institute Members with a diverse range of essential services that enable the synthesis and analysis of biological materials and require sophisticated technical expertise and state-of-the-art instrumentation. In the current period, the mission of this Core was modified as part of a larger reorganization plan. First, all DNA-related activities were outsourced or moved to the Koch Institute Genomics Core, thereby allowing the Biopolymers & Proteomics Core to specialize in protein, proteomic and mass spectrometry services. Second, these capabilities were expanded and enhanced by: moving into a larger, custom-designed space; the acquisition of extensive new instrumentation; and the recruitment of an expert Mass Spectrometry Consultant who provides customized technical support and/or training for high-end proteomics projects. Importantly, the Core is used by more than 80% of the Center Members, including investigators from all four programs. Thus, this Shared Resource is essential to the success of the Koch Institute mission. In the upcoming period, this Core will continue to offer a wide range of state-of-the-art technologies to support the research programs of Center Members. Notably, the requested CCSG budget for Year 44 is only two thirds of the requested and recommended budget in Year 39.