Eunice Kennedy Shriver NICHD Maternal Fetal Medicine Units Network

尤尼斯·肯尼迪·施赖弗 (Eunice Kennedy Shriver) NICHD 母胎医学单位网络

• 批准号: 8638045
• 负责人: Suneet P Chauhan
• 金额: $ 28.72万
• 依托单位: UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON
• 依托单位国家: 美国
• 财政年份: 2001
• 资助国家: 美国
• 起止时间: 2001-04-01 至 2016-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8638045
• 关键词: Address; African American; American College of Obstetricians and Gynecologists; Ancillary Study; Area; Authorship; Birth; Caring; Caucasians; Caucasoid Race; Certification; Child; Clinical; Clinical Research; Clinical Trials; Collaborations; Commit; Data; Data Quality; Dedications; Discipline of obstetrics; Educational workshop; Enrollment; Environment; Faculty; Funding; Future; General Hospitals; Gestational Diabetes; Goals; Health; High birth weight infant; Hispanics; Hospitals; Human Resources; Improve Access; Informatics; Institutional Review Boards; Intervention; Leadership; Letters; Location; Manuscripts; Medical center; Mission; Multi-Institutional Clinical Trial; National Children' s Study; National Institute of Child Health and Human Development; Newborn Infant; Nurses; Nursing Research; Nursing Staff; Outcome; Outpatients; Pathogenesis; Patients; Perinatal; Physicians; Pre-Eclampsia; Pregnancy; Pregnant Women; Premature Birth; Prevention; Prevention strategy; Principal Investigator; Procedures; Productivity; Publications; Qualifying; Recruitment Activity; Research; Research Infrastructure; Research Personnel; Resources; Services; Site; Specialist; Surgeon; Teaching Hospitals; Texas; Universities; Woman; autoimmune lymphoproliferative syndrome; base; comparative effectiveness; disability; experience; falls; fetal; fetal medicine; follow-up; improved; innovation; medical complication; medical schools; member; operation; patient population; public health relevance; racial and ethnic; screening; skills; symposium; unborn child

DESCRIPTION (provided by applicant): The Maternal-Fetal Medicine Division at the University of Texas Medical School at Houston (UT-Houston) is reapplying for its third cycle of participation in the NICHD MFMU Network (initially funded 6/2001). Dr. Susan Ramin, the original PI, became OB/GYN Chair in 10/2006 and Dr. Sean Blackwell was recruited to UT-Houston to serve as PI starting in 6/2007. Dr. Blackwell brings experience within the MFMU Network (prior WSU Alternate-PI 2003-2006), innovation, and unique expertise as the PI. Importantly, he has successfully demonstrated his leadership skills during the transition by improving data quality and increasing subject recruitment/retention. The MFMU Network at UT-Houston conducts the majority of its operations at its two university-affiliated teaching hospitals: Memorial Hermann Hospital (4,800 annual deliveries) and Lyndon B. Johnson General Hospital (3,800 annual deliveries). The administrative and physician leadership at both locations have provided unobstructed access to potential subjects, high-quality research space, and a "culture of research." Collaborations with private OB/GYN physicians and UT faculty have been strengthened and resulted in _ improved access for out-patient studies. The UT-Houston MFM research infrastructure also supports other on-going NICHD multi-center studies including Pathogenesis of Preeclampsia Network, GPN Network, and the National Children's Study. This application describes the track record of recruitment and retention (including long-term follow-up), the expertise and productivity of our MFM faculty, and the scientific contributions of UT-Houston to the MFMU Network. We describe a concept study that addresses a significant health problem (gestational diabetes and fetal overgrowth), which is innovative and demonstrates our understanding of the necessary considerations and approach needed in conducting large, multi-center, clinical trials. UT-Houston has the available patient population, institutional resources, and dedication of a highly- qualified PI to contribute to the mission of the MFMU for the next cycle and beyond.

描述（由申请人提供）：休斯顿得克萨斯大学医学院（UT-休斯顿）的母胎医学部正在重新申请参加NICHD MFMU网络的第三个周期（最初资助6/2001）。最初的PI Susan拉明博士于2006年10月成为OB/GYN主席，Sean Blackwell博士于2007年6月被招募到UT-休斯顿担任PI。Blackwell博士作为PI带来了MFMU网络（之前的WSU Alternate-PI 2003-2006）内的经验、创新和独特的专业知识。重要的是，他通过提高数据质量和增加受试者招募/保留，在过渡期间成功展示了他的领导能力。 UT-休斯顿的MFMU网络在其两所大学附属教学医院进行大部分业务：纪念赫尔曼医院（每年4,800次分娩）和林登B。约翰逊总医院（每年接生3 800例）。两个地点的行政和医生领导层为潜在的研究对象提供了畅通无阻的通道，高质量的研究空间和“研究文化”。“与私人妇产科医生和UT教师的合作得到了加强，从而改善了门诊研究的机会。UT-休斯顿MFM研究基础设施还支持其他正在进行的NICHD多中心研究，包括先兆子痫网络，GPN网络和国家儿童研究的发病机制。 该应用程序描述了招聘和保留（包括长期跟踪），我们的MFM教师的专业知识和生产力的跟踪记录，以及UT-休斯顿对MFMU网络的科学贡献。我们描述了一个概念研究，解决了一个重大的健康问题（妊娠期糖尿病和胎儿过度生长），这是创新的，并表明我们的理解进行大型，多中心，临床试验所需的必要考虑和方法。 UT-休斯顿拥有可用的患者人群、机构资源和高素质PI的奉献精神，可为MFMU的下一个周期及以后的使命做出贡献。