Tulane National Primate Research Center

申请者描述(由申请人提供)：本申请请求为杜兰国家灵长类动物研究中心(TNPRC)从2013年5月1日至2018年4月30日的五年期间提供资金。资金将用于支持该中心的管理、运营、兽医资源、科研资源、试点研究计划、改进和现代化、外联以及教育和培训活动。近三十年来，TNPRC研究项目的主要重点一直是传染病。此外，还开发了一个再生医学项目，该项目与杜兰大学干细胞研究和再生医学中心密切相关。目前，为传染病项目提供资金的主要特定制剂领域是艾滋病、莱姆病、结核病和生物防御相关制剂。这些是多学科研究，涉及TNPRC几个部门的调查人员和中心外的合作者。这些研究的共同之处是关注疾病的发病机制，并利用这些发现为疫苗、诊断和治疗的发展提供信息。再生医学项目允许采用新的方法来治疗许多类型的疾病，为我们的研究项目提供了多样性，并提供了与大学其他部门的重要联系。自2007年5月底上次提交TNPRC基本赠款以来，该中心一直处于显著增长和变化时期。由个人调查员发起的奖励资金翻了一番，完成了三栋新楼，其中一栋是区域生物安全实验室；一个大型生物安全三级设施。TNPRC是唯一拥有区域生物安全实验室的NPRC。我们还扩大了我们的南校区，以允许非人类灵长类繁殖群体未来的增长。 根据资助期的进展，我们对未来持乐观态度。我们可以利用的优势包括：在与NIH和国家优先事项相匹配的研究领域的独特资源和能力，教师任命，强大和多样化的研究资源，有才华和敬业精神的工作人员，与地区大学的良好互动和合作，以及与我们的主办机构以及州和联邦立法者的良好关系。

DESCRIPTION (provided by applicant): This application requests funding for the Tulane National Primate Research Center (TNPRC) for the five year period beginning May 1, 2013 through April 30, 2018. Funds will be used to support the administration, operations, veterinary resources, scientific research resources, pilot research program, improvements and modernization, outreach, and education and training activities of the Center. For nearly three decades, the main focus of the TNPRC research program has been infectious diseases. In addition, a program in regenerative medicine has developed, which Is closely linked to the Center for Stem Cell Research and Regenerative Medicine at Tulane. The major agent-specific areas of funding for the infectious diseases program are currently AIDS, Lyme disease, tuberculosis and biodefense-related agents. These are multidisciplinary studies involving investigators in several Divisions at the TNPRC and collaborators outside the Center. Common to these studies is a focus on disease pathogenesis and on using such findings to inform the development of vaccines, diagnostics and therapeutics. The regenerative medicine program allows novel approaches to the treatment of many types of disease, provides diversity to our research program, and provides an important link to the rest of the university. The period since the last submission of the TNPRC base grant, at the end of May 2007, has been a time of significant growth and change at the Center. Individual investigator-Initiated award funding has doubled and three new buildings have been completed, one of which is a Regional Biosafety Laboratory; a large biosafety level 3 facility. The TNPRC is the only NPRC to have a Regional Biosafety Laboratory. We have also expanded our South Campus to allow future growth of the nonhuman primate breeding colony. Based on the progress in the funding period, we are optimistic about the future. Strengths on which we can capitalize Include unique resources and capabilities In research areas that match NIH and national priorities, faculty appointments, strong and diverse research resources, a talented and dedicated staff, excellent interactions and collaborations with area universities and an outstanding relationship with our host institution and state and federal legislators.