Delaware/Christiana Care community Oncology Research Program

描述(由申请人提供)：特拉华州/克里斯蒂安娜关怀(CCHS)社区肿瘤学研究计划最初是作为社区临床肿瘤学计划(CCOP)于1987年资助的，从2007年开始作为NCI社区癌症中心计划资助，并一直是这两个计划的模范贡献者。目前，CCHS参加了NRG、联盟、ECOG-ACRIN、维克森林和罗切斯特合作小组。CCOP继续履行合作组织遗产组织的研究义务，这些组织包括：CALGB、NSABP、ECOG、RTOG、GOG、维克森林和URCC。CTSU的参与是积极和持续的。我们广阔的集水区包括整个特拉华州以及新泽西州、马里兰州东北部和宾夕法尼亚州东南部(特拉华州和切斯特县)的部分地区。特拉华州在所有癌症部位疾病发病率方面在全国排名第三，马里兰州排名第35，新泽西州排名第5，宾夕法尼亚州排名第6(2007年数据)。我们的研究基础代表着超过200万人的人口基础，具有广泛的协议输入潜力。在首席研究员史蒂芬·S·格拉布斯医学博士、医学博士格雷戈里·马斯特斯、医学博士兼联合首席研究员坎迪·邓普西的领导下，医学硕士、RN、OCN、主任、CCOP调查员、项目协调员和数据经理将继续参与国家临床试验网络(NCTN)核心委员会和领导职位。我们的使命是继续为治疗和癌症控制研究提供收益，并进一步发展癌症护理提供研究(CCDR)的参与，这将建立在我们与NCCCP合作制定的倡议的基础上。我们预计将至少10%的活动用于CCDR，包括对社会因素、组织结构和流程、医疗技术、获得癌症护理的机会、质量和成本因素以及社区差异的复杂情况进行科学调查。并将审查作为CCDR计划一部分的护理和卫生技术系统的财务成本的可行性。这笔赠款的总体影响将是确保CCOP活动的持续和刺激扩大，包括克里斯蒂娜保健保健服务及其附属机构在整个集水区的治疗和癌症控制研究。特拉华州/CCHS CCOP的临床试验收益一直位居全国前列。在过去三年中，2010年、2011年和2012年的应计利率分别为24.8%、24%和21.4%。

DESCRIPTION (provided by applicant): Delaware/Christiana Care (CCHS) Community Oncology Research Program was originally funded as a Community Clinical Oncology Program (CCOP) in 1987, and was funded as a NCI Community Cancer Centers Program beginning in 2007 and has been an exemplary contributor to both programs. Currently, CCHS participates in the NRG, ALLIANCE, ECOG-ACRIN, Wake Forest and Rochester cooperative groups. The CCOP continues to fulfill research obligations for the cooperative group legacy groups including: CALGB, NSABP, ECOG, RTOG, GOG, Wake Forest and URCC. Participation in CTSU is active and ongoing. Our extensive catchment area includes all of Delaware and portions of New Jersey, northeastern Maryland and southeastern Pennsylvania (Delaware and Chester counties). Delaware ranks 3rd in the nation for all cancer site disease incidence, Maryland ranks 35th, New Jersey 5th and Pennsylvania 6th (2007 uses Data). Our research base represents a population base in excess of 2 million people with extensive protocol entry potential. Under the leadership of Stephen S.Grubbs, M.D., Principal Investigator, Gregory Masters, M.D, Co-Principal Investigator and Kandie Dempsey, MS, RN, OCN, Director, CCOP investigators, project coordinators and data managers will continue to participate in National Clinical Trial network (NCTN) core committees and leadership positions. Our mission is to continue accruals to both treatment and cancer control studies and to further develop Cancer Care Delivery Research (CCDR) participation which will build upon the initiatives set forth with our collaboration in NCCCP. We anticipate dedicating at minimum 10% of our activities towards CCDR to include scientific investigation of the complexities of social factors, organizational structures and processes, health technologies, access to cancer care, quality and cost factors, disparities in our community. And will examine the feasibility of examining financial costs of care and health technology systems as part of the CCDR program. The overall impact of this grant will be to ensure continuation and stimulate expansion of CCOP activities, including treatment and cancer control research, at Christiana Care Health Services and its affiliates throughout the catchment area. The Delaware/CCHS CCOP has consistently rated amongst top in the nation for clinical trial accruals. Over the past three years the accrual rate has been 24.8% in 2010, 24% in 2011 and 21.4% in 2012.