1st World Congress on Tourette Syndrome and Tic Disorders

 描述(申请人提供)：多发性抽动症(TS)是一种发育性神经精神障碍，特征是持续的(慢性)运动和声音痉挛，从童年开始，典型的严重程度随着时间的推移而消长。TS往往与强迫症(OCD)和注意力缺陷多动障碍(ADHD)等其他神经精神障碍并存，在儿童和青少年时期经常导致严重的社会、学术和职业疾病，严重时可导致终生残疾。曾经被认为是罕见的TS，现在被认为每1000名儿童中有3-8人发生(0.3-0.8%)。尽管在TS流行病学、遗传学、神经生理学和神经影像方面取得了重大进展，但抽搐和TS的潜在病理生理学仍不清楚。发展对TS的综合理解的一个主要障碍是缺乏一个定期的论坛，让工作在TS研究不同领域的研究人员聚集在一起，交换想法，并建立新的、跨学科的合作，这可能导致研究这种疾病的新方法，从而导致新的治疗方法。本申请申请资助将于2015年6月24-26日在英国伦敦举行的首届抽动症和抽动障碍世界大会的部分资金。鉴于美国和欧洲对TS及相关障碍的认识和兴趣日益增加，TSA已与英国Tourette Action-UK和欧洲抽动症研究学会(ESSTS)合作，就TS及相关障碍的治疗策略和研究取得的最新进展展示了真正的全球视角。因此，首届多发性抽动症和抽动障碍世界大会将取代1981年至2009年期间举行的5次抽动症国际科学研讨会，这些研讨会由TSA、NINDS、NIMH和ORD共同主办。在欧洲举办这次大会将最大限度地促进美国和欧洲TS专家之间的跨文化讨论。此外，大会将成为致力于TS的临床医生和研究人员进行国际交流的高效场所，这将建立全球伙伴关系，汇集资源，并为未来的TS研究努力和改善临床护理设定议程。

 DESCRIPTION (provided by applicant): Tourette Syndrome (TS) is a developmental neuropsychiatric disorder characterized by persistent (chronic) motor and vocal tics that begin in childhood and typically wax and wane in severity over time. TS often co- occurs with other neuropsychiatric disorders such as obsessive-compulsive disorder (OCD) and attention- deficit hyperactivity disorder (ADHD), and together they frequently cause significant social, academic and vocational morbidity in childhood and adolescence, and in severe cases can result in lifelong disability. Once considered to be rare, TS is now believed to occur in 3-8 per 1000 children (0.3-0.8%). Despite significant research advances in TS epidemiology, genetics, neurophysiology and neuroimaging, the underlying pathophysiology of tics and TS is still obscure. A major obstacle to developing an integrated understanding of TS is the absence of a regular forum for investigators working in different areas of TS research to convene together, to exchange ideas, and to establish new, inter-disciplinary collaborations that may result in novel approaches to studying the disorder and therefore lead to new treatments. This application requests funding for partial support for the 1st World Congress on Tourette Syndrome and Tic Disorders to be held in London, England from June 24 - 26, 2015. Given the increased awareness and interest in TS and related disorders across both the US and Europe, TSA has partnered with Tourette Action - UK and the European Society for the Study of Tourette Syndrome (ESSTS) to present a truly global perspective on the most recent advances that have been made in treatment strategies and research in TS and related disorders. As such, the 1st World Congress on Tourette Syndrome and Tic Disorders will supersede the 5 previous International Scientific Symposia on Tourette Syndrome that took place between 1981 and 2009 and were co- sponsored by TSA, NINDS, NIMH and ORD. Holding this congress in Europe will maximize cross-cultural discussion between US and European TS experts. In addition, the congress will serve as a highly effective venue for international communication of clinicians and researchers working on TS that will build global partnerships, pool resources and set the agenda for future TS research efforts and improved clinical care.