1st World Congress on Tourette Syndrome and Tic Disorders

 描述（由申请人提供）：Tourette综合征（TS）是一种发育性神经精神障碍，其特征为开始于儿童期的持续性（慢性）运动和发声抽搐，严重程度通常随时间推移而加重和减轻。TS通常与其他神经精神障碍如强迫症（OCD）和注意力缺陷多动障碍（ADHD）共同发生，并且它们一起经常在儿童和青少年中引起显著的社会、学术和职业发病率，并且在严重的情况下可导致终身残疾。TS曾经被认为是罕见的，现在认为每1000名儿童中有3-8名（0.3-0.8%）发生。尽管在TS流行病学、遗传学、神经生理学和神经影像学方面取得了显著的研究进展，但抽动和TS的潜在病理生理学仍然不清楚。发展综合理解TS的一个主要障碍是缺乏一个定期的论坛，研究人员在不同领域的TS研究召集在一起，交流思想，并建立新的，跨学科的合作，可能会导致新的方法来研究疾病，从而导致新的治疗方法。本申请要求为将于2015年6月24日至26日在英国伦敦举行的第一届抽动秽语综合征和抽动障碍世界大会提供部分支持。鉴于美国和欧洲对TS和相关疾病的认识和兴趣增加，TSA与Tourette Action - UK和欧洲Tourette综合征研究学会（ESSTS）合作，就TS和相关疾病治疗策略和研究的最新进展提出真正的全球观点。因此，第一届世界抽动秽语综合征和抽动障碍大会将取代1981年至2009年期间举行的5次抽动秽语综合征国际科学研讨会，这些研讨会由TSA，NINDS，NIMH和ORD共同赞助。在欧洲举行这次大会将最大限度地提高美国和欧洲TS专家之间的跨文化讨论。此外，大会将作为临床医生和研究人员在TS方面进行国际交流的高效场所，这将建立全球伙伴关系，汇集资源，并为未来的TS研究工作和改善临床护理制定议程。

 DESCRIPTION (provided by applicant): Tourette Syndrome (TS) is a developmental neuropsychiatric disorder characterized by persistent (chronic) motor and vocal tics that begin in childhood and typically wax and wane in severity over time. TS often co- occurs with other neuropsychiatric disorders such as obsessive-compulsive disorder (OCD) and attention- deficit hyperactivity disorder (ADHD), and together they frequently cause significant social, academic and vocational morbidity in childhood and adolescence, and in severe cases can result in lifelong disability. Once considered to be rare, TS is now believed to occur in 3-8 per 1000 children (0.3-0.8%). Despite significant research advances in TS epidemiology, genetics, neurophysiology and neuroimaging, the underlying pathophysiology of tics and TS is still obscure. A major obstacle to developing an integrated understanding of TS is the absence of a regular forum for investigators working in different areas of TS research to convene together, to exchange ideas, and to establish new, inter-disciplinary collaborations that may result in novel approaches to studying the disorder and therefore lead to new treatments. This application requests funding for partial support for the 1st World Congress on Tourette Syndrome and Tic Disorders to be held in London, England from June 24 - 26, 2015. Given the increased awareness and interest in TS and related disorders across both the US and Europe, TSA has partnered with Tourette Action - UK and the European Society for the Study of Tourette Syndrome (ESSTS) to present a truly global perspective on the most recent advances that have been made in treatment strategies and research in TS and related disorders. As such, the 1st World Congress on Tourette Syndrome and Tic Disorders will supersede the 5 previous International Scientific Symposia on Tourette Syndrome that took place between 1981 and 2009 and were co- sponsored by TSA, NINDS, NIMH and ORD. Holding this congress in Europe will maximize cross-cultural discussion between US and European TS experts. In addition, the congress will serve as a highly effective venue for international communication of clinicians and researchers working on TS that will build global partnerships, pool resources and set the agenda for future TS research efforts and improved clinical care.