Training Program in Hypertension, Kidney Disease & Cell Biology

描述（由申请人提供）：本申请为肾脏疾病、高血压和细胞生物学的跨学科研究培训项目提供持续资助。该项目的目的是为有兴趣从事肾脏疾病、血压调节和与肾脏生理和疾病相关的细胞生物学基本方面的研究事业的年轻临床医生和科学家提供培训。该计划的目标是：1)识别和招募优秀的实习生，包括性别和种族，希望获得与肾脏疾病，高血压和细胞生物学相关的基础和应用研究的原理和技术的全面知识；2)提供设计和实施高质量研究项目的培训，包括参与跨学科研究团队；3)提供多学科和综合的指导研究经验，促进学员的职业发展；4)增加训练有素的肾脏相关疾病研究人员的数量，他们将创建自我维持的创新研究项目，并有效地参与肾脏研究相关的培训。受训者将从泌尿外科、儿童肾病学、肾病学和基础科学项目中被吸引。该计划的主要主题是提供一种手段，使积极进取的年轻医生和科学家能够在成熟和富有成效的教师导师的指导下进行密集和持续的研究培训。除主要导师外，所有受训者还将有一个指导委员会。具体的培训机会包括基础和应用细胞生物学、高血压心血管和肾脏系统异常、肾脏发育生物学、泌尿生殖系统癌生物学、肾脏免疫紊乱、肾脏和泌尿道疾病的临床和转化研究等领域。在生理学、生物化学、药理学和免疫学等相关领域提供额外的机会。此外，申请人将有机会与使用流行病学和统计方法的调查人员一起工作。30多名教师表示愿意参与培养这些博士后候选人。广泛的高度专业化的专业知识允许在几乎任何与肾脏疾病有关的领域进行此类培训。

DESCRIPTION (provided by applicant): This application proposes continued funding for an interdisciplinary research training program in kidney diseases, hypertension, and cell biology. The purpose of this program is to provide training for young clinicians and scientists interested in pursuing research careers involved in diseases of the kidney, regulation of the blood pressure, and basic aspects of cell biology as they relate to kidney physiology and disease. The goals of the program are 1) To identify and recruit outstanding trainees, inclusive of gender and ethnicity, who wish to obtain comprehensive knowledge of the principles and techniques of basic and applied research related to kidney disease, hypertension, and cell biology; 2) To offer training in the design and implementation of high quality research projects, including participation in cross-disciplinary research teams; 3) To provide multidisciplinary and integrated mentored research experiences which facilitate developing a trainee's professional career; 4) To increase the pool of well- trained researchers in diseases relating to the kidney who will create self-sustaining, innovative research programs and effectively participate in training related to kidney research. Trainees will be attracted from programs in urology, pediatric nephrology, nephrology, and the basic sciences. The major theme of the program is to provide the means whereby highly motivated young physicians and scientists can spend an intensive and sustained period of research training under the guidance of an established and productive faculty mentor. All trainees will have a mentoring committee in addition to their primary mentor. Specific training opportunities include the areas of basic and applied cell biology, abnormalities of the cardiovascular and renal systems in hypertension, developmental biology of the kidney, the biology of urogenital cancer, immunological disorders of the kidney, and clinical and translational investigation of diseases of the kidney and urinary tract. Additional opportunities will be available in related areas of physiology, biochemistry, pharmacology, and immunology. In addition, applicants will have the opportunity to work with investigators using epidemiologic and statistical methods. Over 30 faculty have indicated a willingness to participate in the trainin of such postdoctoral candidates. A broad range of highly specialized expertise permits such training in almost any area related to kidney diseases.