IGF::OT::IGF HISPANIC COMMUNITY HEALTH STUDY - STUDY OF LATINOS - FIELD CENTER - TASK ORDER 02 - 6/1/14 - 5/31/15

该合同将拉美裔社区健康研究-拉丁裔研究(HCHSSOL)从2013年6月1日延长至2019年5月31日。更新HCHS-SOL的科学目的是：(1)确定拉美裔美国人中高度流行的疾病和状况(如糖尿病、左心室肥厚和妊娠期糖尿病)的推定原因；(2)描述与移民、文化适应和在美国生活的时间相关的健康相关风险和保护因素的转变；以及(3)评估社会经济因素、文化价值观、危险行为和医疗保健获得方式的变化对拉美裔美国人健康的影响。 上述目标将通过国家心肺血液研究所(NHLBI)与四个现场中心、一个协调中心和一个超声心动图阅读中心签订合同来实现。协调中心将根据需要为中心实验室提供服务。研究方案将由一个指导委员会指导，该委员会由每个外地中心、协调中心、 超声心动图读数中心和NHLBI合同官员代表(COR)。要约人将根据他们对最佳方法的评估提交一份建议书。然而，授予后，研究指导委员会将制定标准化的方案，这些方案可能与个别要约人提出的方案相似，也可能不同。

This contract will extend the Hispanic Community Health Study – Study of Latinos (HCHSSOL) from June 1, 2013 through May 31, 2019. The scientific aims of the renewal of the HCHS‐SOL are to: (1) identify putative causes for diseases and conditions highly prevalent in Hispanics (e.g. diabetes, , left ventricular hypertrophy, and gestational diabetes mellitus); (2) describe the transformation of health‐related risk and protective factors related to migration, acculturation, and length of time living in the U.S.; and (3) assess the impact of changes in socioeconomic factors, cultural values, risk behaviors, and medical care access on health in Hispanics. The aims stated above will be accomplished through contracts by the National Heart, Lung, and Blood Institute (NHLBI) with four Field Centers, one Coordinating Center and an Echocardiography Reading Center. The Coordinating Center will provide the services for a Central Laboratory as needed. Study protocols will be directed by a Steering Committee consisting of the Principal Investigator of each Field Center, the Coordinating Center, the Echocardiogram Reading Center and the NHLBI Contracting Officer’s Representative (COR). Offerors will submit a proposal based on their assessment of the optimal methods. However, after award, standardized protocols will be established by the study Steering Committee, which may be similar or different from those proposed by individual Offerors.