HCHS-SOL AE FIELD CENTER DIVERSITY SUPPLEMENT FOR DR. TREJO

HCHS-SOL AE 现场中心多样性补充 DR.

• 批准号: 10953884
• 负责人: ROBERT KAPLAN
• 金额: $ 10.89万
• 依托单位: ALBERT EINSTEIN COLLEGE OF MEDICINE
• 依托单位国家: 美国
• 财政年份: 2023
• 资助国家: 美国
• 起止时间: 2023-03-15 至 2023-11-29
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10953884
• 关键词: HCHS; SOL; AE; FIELD; CENTER

The primary goals for the HCHS baseline study are to examine the prevalence and development of disease in Hispanics/Latinos, the role of acculturation, and to identify risk factors that play protective or harmful roles in Hispanics/Latinos. This project will leverage the HCHS data to examine the genetic risk of suspected nonalcoholic fatty liver disease in Hispanic/Latino populations and to examine differences by genetic ancestry. It will expands on previous HCHS work in the area of the genetics of liver disease, while making the novel contribution of a multicohort pooling project to enhance statistical power and increase generalizability of findings. Dr. Trejo's specific research activities for this supplemental application will involve conducting data analyses, manuscript preparation using data available from the parent study, and genetic data management and analysis that will expand on his previous work.

HCHS基线研究的主要目标是检查拉美裔/拉美裔疾病的流行和发展、文化适应的作用，并确定在拉美裔/拉美裔中发挥保护或有害作用的风险因素。该项目将利用HCHS数据来检查西班牙裔/拉丁裔人群中疑似非酒精性脂肪性肝病的遗传风险，并检查遗传血统的差异。它将在以前HCHS在肝病遗传学领域的工作的基础上进行扩展，同时做出多队列汇集项目的新贡献，以增强统计能力和增加研究结果的概括性。特雷霍博士对这一补充应用程序的具体研究活动将包括进行数据分析、使用从父母研究中获得的数据准备手稿以及基因数据管理 和分析，这将在他之前的工作基础上进行扩展。