Simulation-based Research to Enhance Patient Safety in Radiation Oncology

描述（由申请人提供）：总体目标是开发和评估标准化和可推广的基于模拟的培训（具体目标#1）以及用户界面和认知工作流程增强（具体目标#2）对放射治疗（RT）提供者的性能和精神负荷的影响。基本原理：据估计，在美国每年接受放射治疗（RT）的> H600，000名患者中，高达H5%的患者发生放射治疗（RT）错误; 1，000 - 10，000名患者中有H1发生严重/致命事件。RT中相对较高的错误率和灾难性事件的可能性非常令人担忧，并强调了需要解决的性能和心理工作负荷的潜在系统性挑战。因此，这项研究的结果将对大量患者产生直接影响。研究方法： 受试者随机接受（与不接受）基于模拟的培训，并接受“当前”与“增强”用户界面和认知工作流程，将进行术前和术后评估，以量化这些干预措施对RT提供者的表现和精神负荷的影响。使用2 x 2平衡随机化设计，我们将使用方差分析（ANOVA）来评估四组（+/-基于模拟的培训，以及“当前”与“增强”用户界面和认知工作流程）的主要和交互效应。研究领域：病人安全，心理负荷，个人表现，模拟。科学学科：认知和行为科学;人为因素。

DESCRIPTION (provided by applicant): The overall goal is to develop and assess the impact of standardized and generalizable simulation-based training (specific aim #1), and user interface and cognitive workflows enhancements (specific aim #2) on radiation therapy (RT) providers' performance and mental workload. Rationale: Errors in Radiation Therapy (RT) are estimated to occur in up to H 5% of the > H600,000 patients receiving RT per year in the US; with serious/lethal events occurring H 1 of 1,000-10,000 patents. The relatively high error rates and the potential for catastrophic events in RT is very concerning, and highlights underlying systematic challenges with performance and mental workload that need to be addressed. Thus, the findings from this study will have direct implications for a large number of patients. Methods: Subjects, randomized to receive (vs. not receive) simulation-based training and to 'current' vs. 'enhanced' user interfaces and cognitive workflows, will have pre- and post- assessments to quantify the impact of these interventions on a RT providers' performance and mental workload. Using a 2 x 2 balanced randomization design, we will use analysis of variance (ANOVA) to evaluate main and interaction effects from the four groups (+/-simulation-based training, and 'current' vs. 'enhanced' user interface and cognitive workflow). Research areas: Patient safety, mental workload, individual performance, simulation. Scientific disciplines: Cognitive and Behavioral Sciences; Human Factors.