SALUD: Study of Disaggregated Latinos in the US to Address Disparities

 描述(申请人提供)：到2060年，三分之一的美国人将是西班牙裔/拉美裔。然而，尽管这一群体有巨大的增长和变化，关于拉美裔/拉丁裔心血管健康的数据仍然很少。对美国三个最大的拉美裔拉美裔/亚群--墨西哥人、波多黎各人和古巴人--心血管疾病(CVD)死亡率的差异更是知之甚少。拉美裔/拉丁裔聚集成一个同质群体掩盖了不同群体之间的重要差异，并导致对心血管疾病风险和后果的不完全了解。本研究试图使用美国国家卫生统计(NCHS)美国多死因数据库(AIM 1)对三个最大的拉美裔/拉丁裔亚群超过10年的心血管疾病死亡率数据进行分类。基于拉美裔/拉丁裔亚群主要心血管疾病危险因素的流行程度不同，我们将进一步按疾病亚型(即缺血性心脏病、中风和心力衰竭)对这些群体的心血管疾病死亡率进行分类，这对公共卫生预防战略(目标2)具有重要意义。最后，我们将测试社会人口因素如何解释观察到的死亡模式(目标3)，其中包括文化适应(以出生和语言衡量)、收入、教育和种族飞地。对不同拉美裔/拉丁裔亚群的心血管疾病病因死亡率的研究将解决目前消除这一重要且不断增长的美国少数群体所经历的健康差距所必需的知识方面的一个重要差距。

 DESCRIPTION (provided by applicant): By 2060, one in three Americans will be of Hispanic/Latino origin. However, despite the tremendous growth and variation in this population, data on the cardiovascular health of Hispanics/Latinos remains scarce. Even less is known about the differences in cardiovascular disease (CVD) mortality among the three largest Hispanic Latino/subgroups in the U.S. - Mexicans, Puerto Ricans, and Cubans. The aggregation of Hispanics/Latinos into one homogenous group has masked important differences between the diverse groups, and has led to an incomplete understanding of CVD risks and outcomes. The present study seeks to disaggregate over 10 years of CVD mortality data for the three largest Hispanics/Latino subgroups using the National Health Statistics (NCHS) U.S. Mortality Multiple Cause-of-Death database (Aim 1). Based on the observation that the prevalence of major CVD risk factors differs by Hispanic/Latino subgroups, we will further disaggregate CVD mortality by disease subtype among these groups (i.e. ischemic heart disease, stroke, and heart failure), with important implications for public health prevention strategies (Aim 2). Finally, we will test how socio-demographic factors including acculturation (measured by nativity and language), income, education, and ethnic enclaves explain the observed mortality patterns (Aim 3). The study of CVD cause-specific mortality by distinct Hispanic/Latino subgroups will address an important gap in current knowledge necessary to eliminate the health disparities experienced by this important and growing U.S. minority group.