Morehouse School of Medicine/Tuskegee University/UAB Comprehensive Cancer Center Partnership

7.项目摘要/摘要： 这一类型-2的应用是为了加强和建立莫尔豪斯之间建立的U54合作伙伴关系 医学院(MSM)、塔斯基吉大学(TU)和UAB综合癌症中心 (UABCCC)。该伙伴关系位于东南部的心脏地带，该地区历史上拥有巨大的 服务不足的非裔美国人群体的总体目标是在研究中实现卓越，重点是 年消除癌症健康差距和减轻服务不足人群的癌症负担 该地区。合作机构拥有独特的优势，在实现 通过综合研究、教育和推广提出的目标。主要目标是加强 富有成效的癌症研究计划，以发展一条研究癌症的种族/少数民族研究管道 在男男性接触者和理工大学进行研究，并增加研究人员对 UAB CCC的癌症差异。伙伴关系有四个核心(行政、外联、研究 教育、规划和评估)；两个完整的研究项目；一个试点研究项目；以及两个共享项目 资源(生物伦理学和生物统计学/生物信息学)。有了这些资产和活动，伙伴关系将：1) 通过完整的项目，确定转移性前列腺癌的分子机制和新的治疗靶点 癌症，这在非裔美国人男性中存在更高的比例，并通过试点项目，使 目前，在UAB CCC为种族/少数民族招募成功的患者导航计划 在MSM和Grady医院实施；2)通过外联核心，应用创新的癌症 MSM、TU和UAB CCC的幸存者护理计划，将社区和卫生系统为基础的患者联系起来 导航员和顾问，以提高对护理的满意度，并实施适合文化的社区 对癌症幸存者和照顾者的健康教育；3)通过研究教育核心，雇用 综合癌症研究教育计划，涉及能力建设和与本科生的联系 以及研究生和初级教员，使他们能够从事癌症研究；以及4)提供 为更多的试点研究项目提供资金。规划与评估核心将持续评估/评估 核心、研究项目和共享资源的结果。生命伦理资源共享将 促进和确保遵守生物伦理原则，解决人际关系中的伦理问题 在机构之间以及机构和社区之间。生物统计学/生物信息学共享 资源将为所有活动提供统计和生物信息学支持。我们将共同努力，为 消除癌症健康差距。

7. PROJECT SUMMARY/ABSTRACT: This type-2 application is to strengthen and build upon the established U54 Partnership between Morehouse School of Medicine (MSM), Tuskegee University (TU), and the UAB Comprehensive Cancer Center (UABCCC). The Partnership, located in the heart of the Southeast, a region with a large, historically underserved, African American population, has the overall goal of attaining excellence in research focused on elimination of cancer health disparities and on reducing the cancer burden among underserved populations in the region. The partnering institutions possess unique strengths that complement each other in achieving the proposed goal through integrated research, education, and outreach. The primary objectives are to enhance productive cancer research programs, to develop a pipeline of racial/ethnic minority investigators in cancer research at MSM and TU, and to increase the level of involvement of investigators conducting research on cancer disparities at the UAB CCC. The Partnership has four Cores (Administrative, Outreach, Research Education, and Planning & Evaluation); two Full Research Projects; a Pilot Research Project; and two Shared Resources (Bioethics and Biostatistics/Bioinformatics). With these assets and activities, the Partnership will: 1) through the full projects, identify molecular mechanisms and new therapeutic targets for metastatic prostate cancer, which is present at a higher rate in African American men, and, through the pilot project, adapt the current, successful patient navigation program for racial/ethnic minority recruitment at the UAB CCC for implementation at the MSM and Grady Hospital; 2) through the Outreach Core, apply an innovative cancer survivor care plan at MSM, TU, and the UAB CCC by linking community- and health system-based patient navigators and advisors to improve satisfaction with care, and implement culturally appropriate community health education for cancer survivors and caregivers; 3) through the Research Education Core, employ an integrated cancer research education program that involves capacity building and linkages to undergraduate and graduate students and junior faculty, allowing them to pursue careers in cancer research; and 4) provide funding for additional Pilot Research projects. The Planning & Evaluation Core will continually assess/evaluate the outcomes of the cores, research projects, and shared resources. The Bioethics Shared Resource will promote and ensure adherence to bioethical principles and address ethical considerations in relationships between the institutions and between the institutions and communities. The Biostatistics/Bioinformatics Shared Resource will deliver statistical and bioinformatics support for all activities. Together, we will contribute to elimination of cancer health disparities.