Morehouse School of Medicine/Tuskegee University/UAB Comprehensive Cancer Center Partnership

7.项目总结/摘要： 这种类型-2应用程序是为了加强和建立在建立U 54伙伴关系之间的莫尔豪斯 医学院（MSM），塔斯基吉大学（TU）和UAB综合癌症中心 （UABCCC）。该伙伴关系位于东南部的中心地带，该地区拥有大型，历史悠久的 服务不足的非洲裔美国人，其总体目标是实现卓越的研究，重点是 关于消除癌症健康差距和减少得不到充分服务的人口的癌症负担的 本地区伙伴机构拥有独特的优势，在实现 通过综合研究、教育和推广实现拟议目标。主要目标是提高 富有成效的癌症研究计划，以开发一个少数种族/少数民族癌症研究人员的管道， 在男男性接触者和TU的研究，并提高调查人员的参与程度进行研究， UAB CCC的癌症差异。该伙伴关系有四个核心（行政、外联、研究 教育，规划和评估）;两个完整的研究项目;试点研究项目;和两个共享 资源（生物伦理学和生物统计学/生物信息学）。通过这些资产和活动，伙伴关系将： 通过完整的项目，确定转移性前列腺的分子机制和新的治疗靶点， 癌症，这是目前在非洲裔美国人的比例较高，并通过试点项目，适应 目前，成功的患者导航计划，用于在UAB CCC招募种族/少数民族， 在男男性接触者和格雷迪医院实施; 2）通过外展核心，应用创新的癌症 通过将社区和卫生系统为基础的患者联系起来，在MSM、TU和UAB CCC实施幸存者护理计划 导航员和顾问，以提高护理满意度，并实施文化上适当的社区 癌症幸存者和护理人员的健康教育; 3）通过研究教育核心， 综合癌症研究教育计划，包括能力建设和联系，以本科 和研究生和初级教师，让他们从事癌症研究的职业;和4）提供 资助更多的试点研究项目。规划和评估核心将持续评估/评估 核心成果、研究项目和共享资源。生物伦理学共享资源将 促进和确保遵守生物伦理原则，并处理关系中的伦理考虑 机构之间以及机构和社区之间的关系。生物统计学/生物信息学共享 资源将为所有活动提供统计和生物信息学支持。我们将共同为 消除癌症健康差距。

7. PROJECT SUMMARY/ABSTRACT: This type-2 application is to strengthen and build upon the established U54 Partnership between Morehouse School of Medicine (MSM), Tuskegee University (TU), and the UAB Comprehensive Cancer Center (UABCCC). The Partnership, located in the heart of the Southeast, a region with a large, historically underserved, African American population, has the overall goal of attaining excellence in research focused on elimination of cancer health disparities and on reducing the cancer burden among underserved populations in the region. The partnering institutions possess unique strengths that complement each other in achieving the proposed goal through integrated research, education, and outreach. The primary objectives are to enhance productive cancer research programs, to develop a pipeline of racial/ethnic minority investigators in cancer research at MSM and TU, and to increase the level of involvement of investigators conducting research on cancer disparities at the UAB CCC. The Partnership has four Cores (Administrative, Outreach, Research Education, and Planning & Evaluation); two Full Research Projects; a Pilot Research Project; and two Shared Resources (Bioethics and Biostatistics/Bioinformatics). With these assets and activities, the Partnership will: 1) through the full projects, identify molecular mechanisms and new therapeutic targets for metastatic prostate cancer, which is present at a higher rate in African American men, and, through the pilot project, adapt the current, successful patient navigation program for racial/ethnic minority recruitment at the UAB CCC for implementation at the MSM and Grady Hospital; 2) through the Outreach Core, apply an innovative cancer survivor care plan at MSM, TU, and the UAB CCC by linking community- and health system-based patient navigators and advisors to improve satisfaction with care, and implement culturally appropriate community health education for cancer survivors and caregivers; 3) through the Research Education Core, employ an integrated cancer research education program that involves capacity building and linkages to undergraduate and graduate students and junior faculty, allowing them to pursue careers in cancer research; and 4) provide funding for additional Pilot Research projects. The Planning & Evaluation Core will continually assess/evaluate the outcomes of the cores, research projects, and shared resources. The Bioethics Shared Resource will promote and ensure adherence to bioethical principles and address ethical considerations in relationships between the institutions and between the institutions and communities. The Biostatistics/Bioinformatics Shared Resource will deliver statistical and bioinformatics support for all activities. Together, we will contribute to elimination of cancer health disparities.