2016 Neurobiology of Cognition Gordon Research Conference & Gordon Research Seminar

描述(由申请人提供)：本提案请求部分支持第四届戈登认知神经生物学研究会议及其为受训者举办的相关戈登研究研讨会。GRC背后的驱动力是分子、细胞电路和系统神经科学领域快速融合的发现，以及在复杂认知任务中同时监控和操纵广泛大脑区域活动的技术发展。这些发展与允许细胞靶向和计算方法的遗传操作相结合，为进化描述神经电路和动力学、神经生理过程和潜在认知功能的计算原理提供了基础。GRC的目标是继续促进在该领域工作的经验科学家和理论家之间在相关分析水平上的沟通和合作，强调最新的发现。相关的GRS在GRC之前举行，旨在为博士后和博士后实习生提供机会交流他们最新的发现和观点，并为他们更深入地参与紧随其后的GRC做好准备。GRC的重要特点之一是几位领先的临床医生和科学家参与其中，他们对脑损伤引起的各种认知障碍具有独特的临床观点，并对他们的工作提供了对正常认知功能的洞察。总体而言，该项目是高度跨学科的，将行为、神经成像、电生理技术和针对特定细胞类型的操作与旨在构建认知操作的现实模型的计算方法结合在一起。会议的形式促进了来自不同视角和分析水平的研究人员和受训人员之间的密集互动，特别是临床医生、实验学家和理论家之间的互动。

DESCRIPTION (provided by applicant): This proposal requests partial support for the fourth Gordon Research Conference (GRC) on the Neurobiology of Cognition and for its associated Gordon Research Seminar (GRS) for trainees. The driving force behind the GRC is the rapid pace of convergent findings in molecular, cellular circuit and systems neuroscience, augmented by technical developments in simultaneously monitoring and manipulating activity across wide brain regions during complex cognitive tasks. These developments combined with genetic manipulations allowing cell-targeting and computational approaches provide the basis for evolving descriptions of neuronal circuits and dynamics, neurophysiological processes and computational principles underlying cognitive functions. The goal of this GRC is to continue promoting communication and collaboration across relevant levels of analysis among empirical scientists and theoreticians working in the field, emphasizing the most recent findings. The associated GRS, held just prior to the GRC, is designed to provide opportunities for doctoral and post-doctoral trainees to communicate their most recent findings and perspectives, and to prepare them for more in-depth participation in the parent GRC that immediately follows. One of the important features of this GRC is participation of several leading clinician-scientists with unique clinical perspective on a variety of cognitive disorders caused by brain damage and insights into normal cognitive function their work provides. Overall, the program is highly interdisciplinary, bringing together behavioral, neuroimaging, electrophysiological techniques and manipulations targeting specific cell types with computational approaches aimed at constructing realistic models of cognitive operations. The format of the meeting promotes intensive interactions among investigators and trainees from different perspectives and analytic levels, and in particular, between clinicians, experimentalists and theorists.