Transient Lighting for Fluorescence Image-Guided Surgery

摘要 我们将开发一种荧光图像引导手术（FIGS）系统， 最佳的无背景性能，无需关闭或降低室内照明。 荧光图像引导手术（FIGS）是一个快速发展的领域，具有广泛的临床应用。 应用，包括实时更有效地去除肿瘤;然而， 照明污染了手术期间从患者发出的荧光信号 procedure.我们正在应用一种称为瞬态照明的新方法， 占空比切换的白色LED，用于室内和术野照明， 不受室内灯光影响的荧光捕获。作为该项目的一部分，OnLume，Inc. 将设计和测试一个原型系统用于外科手术。

Abstract We will develop a fluorescence image guided surgery (FIGS) system that delivers optimum, background-free performance without the need to turn off or lower room lighting. Fluorescence image-guided surgery (FIGS) is a rapidly evolving field with broad clinical applications, including more efficacious removal of tumors in real-time; however, ambient room lighting contaminates the fluorescence signal emitted from the patient during the surgical procedure. We are applying a new method called transient lighting that utilizes high-power - low duty cycle switched white LEDs for room and surgical field illumination allowing for timed fluorescence capture that is not affected by the room lights. As part of this project OnLume, Inc. will design and test a prototype system for surgical applications.