Transient Lighting for Fluorescence Image-Guided Surgery
Transient Lighting for Fluorescence Image-Guided Surgery
批准号:
9202254
负责人:
Adam John Uselmann
金额:
$30.0万
依托单位:
依托单位国家:
美国
项目类别:
财政年份:
2016
资助国家:
美国
项目状态:
已结题
起止时间:
2016-07-21 至 2017-07-20
关键词:
AddressAdoptionAffectAminolevulinic AcidAnimal ExperimentationAnimal ModelAnimalsBoxingCancer ModelClinicalCollaborationsCollectionDarknessDetectionDevelopmentEffectivenessEnvironmentExcisionEyeFluoresceinFluorescenceFluorescent ProbesFrequenciesGoalsGoldGuidelinesHumanImageImage-Guided SurgeryImageryImaging DeviceImaging technologyLaboratory ResearchLightLightingMeasurementMethodsNoiseOperating RoomsOperative Surgical ProceduresOpticsPatientsPerformancePhasePhotonsPhysiologic pulsePublic HealthResearchResearch InstituteSignal TransductionSpeedSystemTechniquesTestingTimeTissuesValidationWorkabstractinganimal imagingbasecancer surgeryclinical applicationcommercializationdesignergonomicsfluorescence imagingfluorescence microscopeimaging systemin vivomalignant breast neoplasmmeetingsmouse modelprototypesealsoftware developmentstandard of caretumor
中文摘要
摘要
我们将开发一种荧光图像引导手术(FICS)系统,它可以提供
无需关闭或调低房间照明即可获得最佳的无背景性能。
荧光图像引导手术是一个发展迅速的领域,具有广阔的临床应用前景。
应用,包括更有效地实时切除肿瘤;然而,环境房间
在手术过程中,灯光会污染病人发出的荧光信号
程序。我们正在应用一种名为瞬变照明的新方法,这种方法利用高功率-低
占空比切换的白色LED,用于房间和外科手术野照明,允许定时
不受房间灯光影响的荧光捕获。作为该项目的一部分,OnLume,Inc.
将设计并测试一个用于外科应用的原型系统。
英文摘要
Abstract
We will develop a fluorescence image guided surgery (FIGS) system that delivers
optimum, background-free performance without the need to turn off or lower room lighting.
Fluorescence image-guided surgery (FIGS) is a rapidly evolving field with broad clinical
applications, including more efficacious removal of tumors in real-time; however, ambient room
lighting contaminates the fluorescence signal emitted from the patient during the surgical
procedure. We are applying a new method called transient lighting that utilizes high-power - low
duty cycle switched white LEDs for room and surgical field illumination allowing for timed
fluorescence capture that is not affected by the room lights. As part of this project OnLume, Inc.
will design and test a prototype system for surgical applications.
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会议论文
Ergonomic fluorescence-guided surgery imaging platform for intraoperative assessment of blood and lymphatic vasculature
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批准号:10249334
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项目类别:
-
资助金额:$82.25万
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财政年份:2016
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负责人:Adam John Uselmann
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依托单位:
Ergonomic fluorescence-guided surgery imaging platform for intraoperative assessment of blood and lymphatic vasculature
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批准号:10082058
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项目类别:
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资助金额:$105.71万
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财政年份:2016
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负责人:Adam John Uselmann
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依托单位:
海外基金