Transient Lighting for Fluorescence Image-Guided Surgery

摘要 我们将开发一种荧光图像引导手术(FICS)系统，它可以提供 无需关闭或调低房间照明即可获得最佳的无背景性能。 荧光图像引导手术是一个发展迅速的领域，具有广阔的临床应用前景。 应用，包括更有效地实时切除肿瘤；然而，环境房间 在手术过程中，灯光会污染病人发出的荧光信号 程序。我们正在应用一种名为瞬变照明的新方法，这种方法利用高功率-低 占空比切换的白色LED，用于房间和外科手术野照明，允许定时 不受房间灯光影响的荧光捕获。作为该项目的一部分，OnLume，Inc. 将设计并测试一个用于外科应用的原型系统。

Abstract We will develop a fluorescence image guided surgery (FIGS) system that delivers optimum, background-free performance without the need to turn off or lower room lighting. Fluorescence image-guided surgery (FIGS) is a rapidly evolving field with broad clinical applications, including more efficacious removal of tumors in real-time; however, ambient room lighting contaminates the fluorescence signal emitted from the patient during the surgical procedure. We are applying a new method called transient lighting that utilizes high-power - low duty cycle switched white LEDs for room and surgical field illumination allowing for timed fluorescence capture that is not affected by the room lights. As part of this project OnLume, Inc. will design and test a prototype system for surgical applications.