1/2 Addressing Rural Cancer Health Disparities: An SCC-SIUSM Partnership

摘要(管理核心) 低收入农村社区的癌症健康差距很大，包括筛查率较低， 发病率增加，检测后期，生存较差，死亡率较高。南伊利诺伊州 大学医学院(SIUSM)及其西蒙斯癌症研究所为中部、南部和 伊利诺伊州的三角洲地区。这些农村社区贫困率较高，医疗服务不足， 癌症发病率和死亡率高得惊人。SIUSM和NCI指定的Siteman癌症中心 圣路易斯华盛顿大学(WUSTL)的(SCC)建立了这一促进癌症的合作伙伴关系 在SIUSM进行研究，减少这些差距。我们在这个P20应用程序中的总体目标是建立癌症 SIUSM的研究能力，支持SIUSM教职员工过渡到NIH资助的癌症差异研究， 并扩大SCC的农村癌症研究范围和活动。我们的目标是促进学员的发展和 这两个机构的初级教员帮助他们发展农村癌症差异研究，并将提供 为所有研究人员提供从事跨机构研究和指导的机会。我们的行政部门 CORE提供领导和管理，帮助我们实现这些目标并发展我们的合作伙伴关系。这 CORE由两名首席调查员领导，由一个代表方案的执行委员会提供支持 来自每个合作伙伴站点的领导者和利益相关者。代表领导层的内部咨询委员会 来自SIUSM、WUSTL和综合癌症中心(SCC)将提供监督、评估和 方向。我们增加了一个社区咨询委员会，以帮助我们确定优先事项和制定 社区参与战略。行政核心目标是：1)推动和实施试点 为研究人员提供研究资金、经验和未来初步数据的研究计划 NIH RO1/R21拨款。该项目于2013年启动，已经将我们的教职员工联系在一起，并正在帮助SIUSM 研究人员建立他们的研究计划，并允许SCC调查人员扩大他们的农村癌症 差异研究。去年，我们在内部资助了一个试点项目；另一个试点项目包括在本申请中。2)SCC 将为SIUSM教员提供学习活动的机会，例如通过视频/网络上行链接分享研讨会。 我们将共同制定短期研究人员交流计划和农村卫生研讨会系列，作为 培训计划的一部分。3)在现有活动的基础上，我们将分享教师早期职业生涯的战略 发展。特别是，WUSTL的公共卫生科学部提供为期10个月的硕士学位 人口健康科学，我们将在其中招收SIUSM教员。SIUSM教职员工将包括在SCC 全面、综合的辅导活动。4)我们将完善我们的评估框架，以衡量 我们的伙伴关系努力的有效性。核心还将努力确保伙伴关系的可持续性，并 通过规划和提交未来的赠款申请来开展活动。总体而言，我们相信这些活动将 在SIUSM创建一个可持续和有效的癌症差异研究计划，并在SCC加强这一计划。

ABSTRACT (ADMINISTRATIVE CORE) Low-income rural communities experience significant cancer health disparities, including lower screening rates, increased incidence, later stage at detection, poorer survival, and higher mortality. The Southern Illinois University School of Medicine (SIUSM) and its Simmons Cancer Institute serve the central, southern, and Delta regions of Illinois. These rural communities have elevated poverty rates, are medically under-served, and have disparately high cancer incidence and mortality. SIUSM and the NCI-designated Siteman Cancer Center (SCC) at Washington University in Saint Louis (WUSTL) established this Partnership to promote cancer research at SIUSM and reduce these disparities. Our overall aims in this P20 application are to build cancer research capacity at SIUSM, support SIUSM faculty in transitioning to NIH-funded cancer disparities research, and expand SCC's rural cancer research reach and activity. We aim to foster the development of trainees and junior faculty at both institutions to help them develop rural cancer disparity research and will provide opportunities for all investigators to engage in cross-institutional research and mentoring. Our Administrative Core provides the leadership and management to help us achieve these goals and grow our Partnership. This Core is led by the two Principal Investigators, supported by an Executive Committee representing Program Leaders and stakeholders from each partner site. An Internal Advisory Committee representing leadership from SIUSM, WUSTL, and the comprehensive cancer center (SCC) will provide oversight, evaluation, and direction. We added a Community Advisory Committee to assist us in setting priorities and developing community engagement strategies. The Administrative Core Aims are: 1) Promote and implement a pilot research program that provides investigators with research funding, experience, and preliminary data for future NIH RO1/R21 grants. This program, initiated in 2013, has already linked our faculty, and is helping SIUSM investigators build their research programs and allowing SCC investigators to expand their rural cancer disparities research. We funded one pilot internally last year; another is included with this application. 2) SCC will provide SIUSM faculty access to learning activities, such as sharing seminars through video/web uplink. Together we will develop a short-term investigator exchange program and a rural health seminar series as part of the Training Program. 3) Building on existing activities, we will share strategies for faculty early career development. In particular, WUSTL's Division of Public Health Sciences offers a 10-month master's degree in Population Health Science, in which we will enroll SIUSM faculty. SIUSM faculty will be included in SCC's comprehensive and integrated mentoring activities. 4) We will refine our evaluation framework to measure effectiveness of our Partnership efforts. The Core will also work to ensure sustainability of the Partnership and activities through planning and submitting future grant applications. In whole, we believe these activities will create a sustainable and effective cancer disparities research program at SIUSM and enhance that at SCC.