1/2 Addressing Rural Cancer Health Disparities: An SCC-SIUSM Partnership

摘要（管理核心） 低收入农村社区经历了显著的癌症健康差异，包括较低的筛查率， 发病率增加，检测时的晚期，生存率降低，死亡率升高。南伊利诺伊 大学医学院（SIUSM）及其西蒙斯癌症研究所服务于中部，南部和南部地区。 伊利诺伊州的三角洲地区。这些农村社区的贫困率较高，医疗服务不足， 癌症发病率和死亡率都非常高。SIUSM和NCI指定的Siteman癌症中心 (SCC)位于圣刘易斯的华盛顿大学（WUSTL）建立了这个伙伴关系，以促进癌症 研究在SIUSM和减少这些差距。我们在这个P20应用程序中的总体目标是建立癌症 SIUSM的研究能力，支持SIUSM教师过渡到NIH资助的癌症差异研究， 并扩大SCC的农村癌症研究范围和活动。我们的目标是促进学员的发展， 这两个机构的初级教师，以帮助他们发展农村癌症差异研究，并将提供 为所有研究人员提供参与跨机构研究和指导的机会。我国行政 核心提供领导和管理，以帮助我们实现这些目标，并发展我们的合作伙伴关系。这 核心研究由两名主要研究者领导，并由代表项目的执行委员会提供支持。 每个合作伙伴站点的领导者和利益相关者。代表领导层的内部咨询委员会 来自SIUSM、WUSTL和综合癌症中心（SCC）的专家将提供监督、评估和 方向我们增加了一个社区咨询委员会，以协助我们确定优先事项和发展 社区参与战略。行政核心目标是：1）促进和实施试点 为研究人员提供研究资金、经验和未来研究的初步数据的研究计划 NIH RO 1/R21赠款。该计划于2013年启动，已经将我们的教师联系起来，并正在帮助SIUSM 研究人员建立他们的研究计划，并允许SCC研究人员扩大他们的农村癌症 差距研究。我们去年在内部资助了一个试点项目;另一个项目也包含在这个应用程序中。2)SCC 将提供SIUSM教师访问学习活动，如通过视频/网络上行链路共享研讨会。 我们将共同开发一个短期的研究人员交流项目和一个农村健康研讨会系列， 的培训计划。3)在现有活动的基础上，我们将分享教师早期职业生涯的策略 发展特别是，WUSTL的公共卫生科学部提供了一个为期10个月的硕士学位， 人口健康科学，我们将招收SIUSM教师。SIUSM教师将被纳入SCC的 全面和综合的辅导活动。4)我们将完善我们的评估框架， 我们的合作伙伴关系的有效性。核心小组还将努力确保伙伴关系的可持续性， 通过规划和提交未来的赠款申请开展活动。总的来说，我们认为这些活动将 在SIUSM创建一个可持续和有效的癌症差异研究计划，并在SCC加强。

ABSTRACT (ADMINISTRATIVE CORE) Low-income rural communities experience significant cancer health disparities, including lower screening rates, increased incidence, later stage at detection, poorer survival, and higher mortality. The Southern Illinois University School of Medicine (SIUSM) and its Simmons Cancer Institute serve the central, southern, and Delta regions of Illinois. These rural communities have elevated poverty rates, are medically under-served, and have disparately high cancer incidence and mortality. SIUSM and the NCI-designated Siteman Cancer Center (SCC) at Washington University in Saint Louis (WUSTL) established this Partnership to promote cancer research at SIUSM and reduce these disparities. Our overall aims in this P20 application are to build cancer research capacity at SIUSM, support SIUSM faculty in transitioning to NIH-funded cancer disparities research, and expand SCC's rural cancer research reach and activity. We aim to foster the development of trainees and junior faculty at both institutions to help them develop rural cancer disparity research and will provide opportunities for all investigators to engage in cross-institutional research and mentoring. Our Administrative Core provides the leadership and management to help us achieve these goals and grow our Partnership. This Core is led by the two Principal Investigators, supported by an Executive Committee representing Program Leaders and stakeholders from each partner site. An Internal Advisory Committee representing leadership from SIUSM, WUSTL, and the comprehensive cancer center (SCC) will provide oversight, evaluation, and direction. We added a Community Advisory Committee to assist us in setting priorities and developing community engagement strategies. The Administrative Core Aims are: 1) Promote and implement a pilot research program that provides investigators with research funding, experience, and preliminary data for future NIH RO1/R21 grants. This program, initiated in 2013, has already linked our faculty, and is helping SIUSM investigators build their research programs and allowing SCC investigators to expand their rural cancer disparities research. We funded one pilot internally last year; another is included with this application. 2) SCC will provide SIUSM faculty access to learning activities, such as sharing seminars through video/web uplink. Together we will develop a short-term investigator exchange program and a rural health seminar series as part of the Training Program. 3) Building on existing activities, we will share strategies for faculty early career development. In particular, WUSTL's Division of Public Health Sciences offers a 10-month master's degree in Population Health Science, in which we will enroll SIUSM faculty. SIUSM faculty will be included in SCC's comprehensive and integrated mentoring activities. 4) We will refine our evaluation framework to measure effectiveness of our Partnership efforts. The Core will also work to ensure sustainability of the Partnership and activities through planning and submitting future grant applications. In whole, we believe these activities will create a sustainable and effective cancer disparities research program at SIUSM and enhance that at SCC.