Research Core

研究核心

• 批准号: 9062328
• 负责人: EDWARD E. PARTRIDGE
• 金额: $ 6.15万
• 依托单位: UNIVERSITY OF ALABAMA AT BIRMINGHAM
• 依托单位国家: 美国
• 财政年份: 2016
• 资助国家: 美国
• 起止时间: 2016-04-01 至 2017-09-21
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/9062328
• 关键词: ARHGEF5 gene; African American; Cardiovascular Diseases; Cell Nucleus; Chronic Disease; Collaborations; Comprehensive Cancer Center; Daughter; Development; Disease; Effectiveness; Extramural Activities; Faculty; Fertilization; Funding; Goals; Historically Black Colleges and Universities; Human Papilloma Virus Vaccine; Immigrant; Institution; Intervention; Knowledge; Latina; Malignant Neoplasms; Nutritional Study; Outcome; Phase; Philanthropic Fund; Pilot Projects; Procedures; Research; Research Activity; Research Infrastructure; Research Project Grants; Resources; Risk Factors; Sample Size; Schools; Scientist; Screening for cancer; Source; Staging; Stroke; Testing; United States National Institutes of Health; Work; base; cancer prevention; cardiovascular disorder risk; data management; diabetes education; disparity reduction; health disparity; improved; innovation; minority health; programs; success; symposium; synergism; uptake

The Research Core will generate new knowledge on minority health and chronic disease, specifically cancer and cardiovascular disease, with emphasis on developing and testing interventions to reduce these disparities. The Core will combine oversight of two P60-supported full research projects with an innovative pilot project program that leverages NIH funding with institutional and philanthropic funding. The Research Core will capitalize on the successful research conducted in the previous two phases of our P60 Center of Excellence, and will make use of the infrastructure of the UAB-supported Minority Health & Health Disparities Research Center (MHRC). Thus it will advance our understanding of health disparities and enhance our efforts to eliminate them. Specific aims are: Aim 1: Oversee the implementation of two full research projects: 1."Promoting HPV Vaccine Uptake among Daughters of Latina Immigrants"; and 2. "Improving Stroke Outcomes for African Americans." Aim 2: Facilitate the development and submission of new research projects on health disparities for extramural funding through: a) Promotion of research consistent with our overall focus (chronic disease, specifically cancer prevention and CVD risk factors and stroke), themes (minority health and health disparities), and emphasis (understanding and intervening); b) Review of and scientific contributions to proposals; c) Statistical and research infrastructure support for proposals (e.g., sample-size computations, analytic plans, and data management procedures). Aim 3: Identify additional resources through the institutionally supported Minority Health & Health Disparities Research Center (MHRC) and in collaboration with other UAB centers and schools to provide funds to junior faculty to conduct pilot projects related to health disparities. We will leverage MHDRC funds with those of the MHRC for a steady state of 2-3 pilot projects annually. Aim 4: Integrate multiple sources of expertise on minority health and health disparities with the research base of the MHDRC for intellectual cross-fertilization and leveraging of resources. Specifically: a) conduct seminars; b) an annual Health Disparities Research Symposium to promote research on health disparities, share knowledge, and cultivate interactions and networking among scientists; and c) direct scientists to other appropriate UAB research resources.

研究核心将产生关于少数民族健康和慢性病，特别是癌症和心血管疾病的新知识，重点是制定和测试干预措施，以减少这些差距。核心将把两个p60支持的全面研究项目的监督与一个创新的试点项目计划结合起来，该项目将利用NIH的资金和机构和慈善资金。研究核心将利用我们的P60卓越中心前两个阶段进行的成功研究，并将利用uab支持的少数民族健康与健康差异研究中心（MHRC）的基础设施。因此，它将促进我们对健康差距的理解，并加强我们消除这些差距的努力。