Animal and Human Imaging Shared Resource

动物和人类成像共享资源

• 批准号: 9152302
• 负责人: Thomas E Yankeelov
• 金额: $ 19.11万
• 依托单位: VANDERBILT UNIVERSITY MEDICAL CENTER
• 依托单位国家: 美国
• 资助国家: 美国
• 起止时间: 至
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/9152302
• 关键词: Address; Animal Cancer Model; Animal Experimentation; Animal Model; Animals; Cancer Center; Cancer Center Support Grant; Clinical; Clinical Trials; Collaborations; Data; Data Analyses; Detection; Development; Ensure; Equipment; Event; Experimental Designs; Faculty; Future; Goals; Histology; Hour; Human; Image; Image Analysis; Imaging Techniques; Individual; Institutes; Institution; Investigational New Drug Application; Magnetic Resonance; Magnetic Resonance Imaging; Malignant Neoplasms; Methods; Mission; Modality; Molecular; Monitor; Nuclear; Operating System; Optics; Patients; Phase; Physicians; Positron-Emission Tomography; Preparation; Production; Productivity; Proteomics; Protocols documentation; Radiochemistry; Radiopharmaceuticals; Research; Research Personnel; Resource Sharing; Resources; Science; Scientist; Talents; Time; Tracer; Translational Research; Ultrasonography; Universities; abstracting; animal imaging; bioimaging; cancer clinical trial; cancer imaging; clinically relevant; imaging probe; imaging system; improved; in vivo; innovation; instrument; meetings; member; method development; non-invasive imaging; novel; pre-clinical; quantitative imaging; research study; response; single photon emission computed tomography; tumor

TRANSLATIONAL RESEARCH GROUP CORE 008 – ANIMAL AND HUMAN IMAGING SHARED RESOURCE PROJECT SUMMARY/ABSTRACT The Animal and Human Imaging Shared Resource (AHISR) has been supported by the Cancer Center Support Grant (CCSG) since 2004. The AHISR provides scientific and technical assistance for experiments employing biomedical imaging to study cancer in both the preclinical and clinical settings, and will undertake developments to meet the needs of the Vanderbilt-Ingram Cancer Center (VICC). The faculty and staff within the AHISR provide access to state-of-the-art imaging facilities including advanced human MRI systems operating at 3T and 7T as well as a comprehensive facility for animal imaging and research radiopharmaceuticals for animal and human use. Furthermore, the AHISR leverages the resources in the VICC with the Vanderbilt University Institute of Imaging Science (VUIIS) to develop new and improved methods for obtaining information that addresses research questions of direct cancer relevance. More specifically, the AHISR provides: 1. Collaborations with expert imaging science faculty (in nuclear, optical, magnetic resonance and ultrasound imaging) for the development and application of cutting-edge imaging protocols 2. Innovative and novel radiopharmaceuticals for animal and human imaging research 3. Support for imaging system operators and technical staff who will handle patient and animal preparation and monitoring as well as operate the instruments 4. Support for data analysis and for quantitative image analysis customized to specific applications, including the co-registration and integration of multiple modalities, histology and proteomics The AHISR brings together expensive equipment and diverse expertise into a comprehensive integrated resource. Supporting a professional staff dedicated to cancer imaging through the AHISR will ensure that the quality of the imaging data, and consequently, the overall quality of studies, is the highest possible.

翻译研究小组 核心008 -动物和人类成像共享资源 项目总结/摘要 动物和人类成像共享资源（AHISR）得到了癌症中心支持 自2004年以来，获得CCSG赠款。AHISR为采用以下技术的实验提供科学和技术援助： 生物医学成像在临床前和临床环境中研究癌症，并将承担 Vanderbilt-Ingram癌症中心（VICC）的需求。学校的教职员工 AHISR提供最先进成像设备，包括先进的人体MRI系统 运行在3 T和7 T以及动物成像和研究的综合设施 动物和人类使用的放射性药物。此外，AHISR利用 VICC与范德比尔特大学成像科学研究所（VUIIS）合作开发新的和改进的 获得解决与癌症直接相关的研究问题的信息的方法。更 具体而言，AHISR提供： 1.与成像科学专家合作（在核，光学，磁共振和 超声成像），用于开发和应用尖端成像协议 2.用于动物和人类成像研究的创新和新型放射性药物 3.为处理患者和动物的成像系统操作员和技术人员提供支持 准备和监测以及操作仪器 4.支持数据分析和针对特定应用定制的定量图像分析， 包括多种模式、组织学和蛋白质组学的共同注册和整合 AHISR将昂贵的设备和各种专业知识汇集到一个全面的集成系统中， resource.通过AHISR支持致力于癌症成像的专业人员将确保 成像数据的质量以及因此研究的总体质量是最高的。