2015 AAOS/ORS Biologic Treatments of Orthopaedic Injuries Research Symposium

2015年AAOS/ORS骨科损伤生物治疗研究研讨会

• 批准号: 8838385
• 负责人: Robert F LaPrade
• 金额: $ 1万
• 依托单位: AMERICAN ACADEMY OF ORTHOPAEDIC SURGEONS
• 依托单位国家: 美国
• 财政年份: 2015
• 资助国家: 美国
• 起止时间: 2015-06-01 至 2016-05-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8838385
• 关键词: Academy; Adipose tissue; Adult; American; Area; Autologous; Blood Platelets; Bone Injury; Bone Marrow; Cells; Clinical; Clinical effectiveness; Collaborations; Communities; Consensus; Development; Exhibits; Florida; Funding Opportunities; Goals; Injury; Journals; Knowledge; Ligaments; Link; Manipulative Therapies; Measurable; Measures; Medical; Mentorship; Mesenchymal; Muscle; Musculoskeletal; Natural regeneration; ORALIT; Orthopedics; Outcome; Participant; Pathway interactions; Patient Care; Patients; Plasma; Publishing; Research; Research Personnel; Scientist; Stem cells; Surgeon; Tendon structure; Therapeutic Uses; Time; Tissues; Translating; Travel; articular cartilage; base; biological research; blood product; cell bank; clinical application; expectation; implantation; improved; meetings; multidisciplinary; musculoskeletal injury; programs; public health relevance; reconstruction; repaired; scaffold; symposium

 DESCRIPTION (provided by applicant): The 2015 AAOS Biologic Treatments for Orthopaedic Injuries (BTOI) research symposium will provide a forum for discussion and collaboration among a multidisciplinary group of basic scientists, clinicians, young investigators, [and registrants] t develop a consensus and identify ways to improve strategies for translational pathways to link current cutting edge biological research to the clinical application of biologic treatments for musculoskeletal injuries Through targeted breakout discussions, program participants and young investigators will exchange information to stimulate new research opportunities and highlight areas of specific needs for improving patient care. Specifically, the BTOI symposium will examine current standards and identify knowledge gaps for the use of autologous blood products such as platelet rich plasma (PRP), the use of minimally manipulated adult progenitor cells, as well as the use of scaffold-based strategies of the repair, reconstruction, and/or regeneration of tendon, ligament, muscle, and articular cartilage tissues. The symposium proceedings will be published and widely disseminated in a relevant orthopaedic journal. An emphasis will placed on mentorship and the establishment of research collaborations and funding opportunities for [up to 15] young investigators (academic orthopaedic clinicians and basic scientists) in a small meeting format [(young investigators will be approximately 20% of total meeting attendees)], including full travel support, with the expectation that the young investigators will present their research to leaders in the field, and networking discussions [to expose the young investigators to leaders in their field].

 描述（申请人提供）：2015年AAOS骨科损伤生物治疗（BTOI）研究研讨会将为基础科学家，临床医生，年轻研究人员，[和注册人]我们不能达成共识，并确定如何改善翻译途径的策略，将当前最前沿的生物学研究与生物制品的临床应用联系起来。通过有针对性的分组讨论，项目参与者和年轻的研究人员将交流信息，以刺激新的研究机会，并强调改善患者护理的特定需求领域。具体而言，BTOI研讨会将检查当前的标准，并确定使用自体血液制品（如富血小板血浆（PRP）），使用最低限度操作的成人祖细胞，以及使用基于支架的策略修复，重建和/或肌腱，韧带，肌肉和关节软骨组织再生的知识差距。专题讨论会的会议记录将在一份有关的骨科杂志上发表并广泛传播。重点将放在指导和建立研究合作以及为[最多15名]年轻研究人员提供资助机会（学术骨科临床医生和基础科学家）在一个小型会议格式[（年轻的研究人员将占与会者总数的约20%）]，包括全额差旅费支持，预计年轻的研究人员将向该领域的领导者介绍他们的研究，和网络讨论[让年轻的研究人员接触他们领域的领导者]。