Innovative Neurophysiological Techniques for Assessing Trunk Muscle Control and Function

用于评估躯干肌肉控制和功能的创新神经生理学技术

• 批准号: 9206585
• 负责人: Brian C Clark
• 金额: $ 18.81万
• 依托单位: OHIO UNIVERSITY ATHENS
• 依托单位国家: 美国
• 财政年份: 2016
• 资助国家: 美国
• 起止时间: 2016-09-01 至 2018-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/9206585
• 关键词: Acupuncture Therapy; Adult; Age; Back Pain; Bilateral; Biofeedback; Biological Neural Networks; Biomechanics; Brain region; Brodmann' s area; Chronic low back pain; Clinical; Cohort Studies; Data; Development; Elderly; Electromyography; Enrollment; Equilibrium; Functional Magnetic Resonance Imaging; Future; Goals; Impairment; Individual; Integrative Medicine; Intervention; Investigation; Link; Low Back Pain; Measures; Mind-Body Intervention; Motor Activity; Movement; Muscle; Muscle function; Musculoskeletal Equilibrium; Nature; Outcome; Outcome Measure; Pain; Participant; Pathology; Pattern; Performance; Physical Function; Physiologic pulse; Physiological; Protocols documentation; Public Health; Quadratus Lumborum Muscle; Relaxation; Reproducibility; Research; Rest; Spinal Manipulation; Tai Ji; Target Populations; Task Performances; Techniques; Testing; Therapeutic; Therapeutic Studies; Time; Variant; Work; Yoga; base; cost; iliacus muscle; improved; innovation; interest; motor control; neurophysiology; neuroregulation; novel; patient population; pilates exercise; primary outcome; research study; tool

GRANT TITLE: Innovative neurophysiological techniques for assessing trunk muscle control and function ABSTRACT Impairments in motor control are linked to low back pain and reductions in physical function in the elderly. Unfortunately, many techniques to assess the neural control of movement are not feasible, or directly applicable, to the trunk musculature. Accordingly, we will develop innovative approaches to study these muscles. Specifically, we will work to develop a reliable, fMRI protocol that investigates the activity of the motor neural networks of selected trunk muscles (specific aim 1). We will also develop a reliable muscle functional MRI (mfMRI) protocol to assess the spatial muscle activation patterns of the deeper lumbopelvic muscles (specific aim 2).We will examine the test-retest reliability of these approaches in four distinct target populations: healthy adults, adults with chronic low back pain, older adults, and older adults with high levels of trunk muscle control (i.e., individuals with expertise in Pilates). By enrolling groups of various levels of trunk muscle control, pathology state and age, we will be able to not only determine the intra-individual reliability, but also the inter-individual reliability as we expect the variability of the measures to be influenced by physical ability, pain state and age. Lastly, in an exploratory aim we will examine the association of our novel neurophysiological measures from Aim 1 and 2 with classic biomechanical and muscle function measures (e.g., trunk extensor strength, trunk extensor force-matching steadiness, and static balance). Successfully developing reliable techniques of this nature will result in new and improved research tools for conducting rigorous studies of therapeutic approaches, such as spinal manipulation and yoga, within the context of trunk muscle control and function.

授权标题：用于评估躯干肌肉控制和功能的创新神经生理学技术