Bangkok Online Testing on MSM

曼谷 MSM 在线测试

• 批准号: 9064254
• 负责人: THOMAS E GUADAMUZ
• 金额: $ 13.83万
• 依托单位: MAHIDOL UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2016
• 资助国家: 美国
• 起止时间: 2016-02-08 至 2018-01-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/9064254
• 关键词: AIDS prevention; Anti-Retroviral Agents; Antibodies; Antigens; Asia; Behavior; Blood; Caring; Chemoprophylaxis; Clinic; Collection; Continuity of Patient Care; Counseling; Country; DNA; Data; Development; Diagnostic; Disease; Early identification; Epidemic; Feasibility Studies; Focus Groups; Funding Mechanisms; Future; HIV; HIV Infections; HIV Seropositivity; Human immunodeficiency virus test; Incidence; Infection; Internet; Interview; Investigation; Laboratories; Liquid substance; Maps; Methods; Modality; Nurses; Oral; Participant; Perception; Persons; Pilot Projects; Prevalence; Process; Professional counselor; Questionnaires; Reading; Recruitment Activity; Reporting; Research Project Grants; Research Proposals; Risk; Risk Reduction; Sampling; Services; Social Network; Spottings; Surveys; Target Populations; Technology; Testing; Thailand; Time; Training; Videoconferences; Videoconferencing; base; experience; follow-up; improved; innovation; insight; men who have sex with men; mobile application; prevent; prevention service; psychosocial; public health relevance; social; symposium; transmission process; uptake; web site; willingness; young men who have sex with men

 DESCRIPTION (provided by applicant): The HIV epidemic is accelerating among young men who have sex with men (YMSM, 18 to 24 years) in Bangkok where HIV incidence was reported to be 8.8 to 12.2 per 100 person-years, the highest such incidence documented in Asia. Engagement and retention of YMSM of unknown or HIV negative serostatus in regular (at least annual) HIV testing is essential for timely linkage to HIV prevention services, such as risk reduction counseling and HIV chemoprophylaxis. Among YMSM unaware of an existing or new HIV infection, timely identification is necessary to increase linkage and initiation of antiretrovial treatment and care to improve disease outlook and prevent onward HIV transmission. However, structural, logistical and psychosocial barriers limit the uptake and retention of Thai MSM in regular HIV testing, hindering the rollout of much needed HIV prevention and treatment services targeting this population. This study proposes the use of online HIV testing (OHT) as an alternative HIV testing modality to increase engagement, retention and linkage of YMSM in HIV prevention, treatment and care services. The specific aims of this research proposal are 1) To qualitatively explore barriers and facilitators to OHT among Bangkok YMSM; 2) To quantitatively examine current perceptions, barriers, facilitators to HIV testing among Bangkok YMSM and estimate the proportion likely to undergo OHT, identify factors associated with willingness to access OHT and to participate in a pilot study of this new HIV testing modality; and 3) To determine the acceptability and feasibility of OHT using a new HIV rapid diagnostic antibody/antigen-based self-test in real time and a self-collected dried blood spot (DBS) with centralized HIV DNA testing. Results of rapid testing will be read- and of centralized testing will be delivered by video conference, followed by discussion, post-test counseling and linkage to care and treatment, in a 6-month pilot study. Particularly, logistical issues, concerns over rapid HIV self-testing, DBS self-collection and laboratory testing, reading or reporting of results by video conferencing will be assessed, as well as how OHT may help to overcome some of the existing barriers to HIV testing. Using new HIV diagnostic and online technologies, OHT may be a promising strategy to increase engagement, retention and linkage to HIV prevention, treatment and care services among Thai YMSM.

 描述（由申请人提供）：在曼谷，艾滋病毒在男男性行为者（YMSM，18至24岁）中的流行正在加速，据报告，艾滋病毒的发病率为每100人年8.8至12.2人，是亚洲记录的最高发病率。在定期（至少每年一次）的艾滋病毒检测中，未知或艾滋病毒阴性血清状态的YMSM的参与和保留对于及时与艾滋病毒预防服务（如降低风险咨询和艾滋病毒化学预防）联系至关重要。在YMSM不知道现有的或新的艾滋病毒感染，及时识别是必要的，以增加联系和启动抗逆转录病毒治疗和护理，以改善疾病的前景，防止艾滋病毒的传播。然而，结构、后勤和心理障碍限制了泰国男男性行为者接受和保留定期艾滋病毒检测，阻碍了针对这一人群的急需的艾滋病毒预防和治疗服务的推出。本研究建议使用在线艾滋病毒检测（OHT）作为一种替代的艾滋病毒检测模式，以增加YMSM在艾滋病毒预防，治疗和护理服务中的参与，保留和联系。本研究计划的具体目标是：1）定性探讨曼谷青年男同性恋者进行OHT的障碍和促进因素; 2）定量研究曼谷青年男同性恋者目前对艾滋病毒检测的看法、障碍和促进因素，估计可能进行OHT的比例，确定与接受OHT的意愿相关的因素，并参与这种新的艾滋病毒检测方式的试点研究;（3）采用一种新的基于抗体/抗原的真实的自我检测方法和一种自我采集的干血斑（DBS）进行HIV DNA集中检测，以确定OHT的可接受性和可行性。快速检测的结果将被读取-集中检测的结果将 在为期6个月的试点研究中，通过视频会议提供培训，然后进行讨论、测试后咨询以及与护理和治疗的联系。特别是，将评估后勤问题、对快速艾滋病毒自我检测、DBS自我采集和实验室检测、阅读或通过视频会议报告结果的关注，以及OHT如何帮助克服艾滋病毒检测的一些现有障碍。利用新的艾滋病毒诊断和在线技术，OHT可能是一个有前途的战略，以增加泰国YMSM之间的艾滋病毒预防，治疗和护理服务的参与，保留和联系。