Bangkok Online Testing on MSM

曼谷 MSM 在线测试

• 批准号: 9064254
• 负责人: THOMAS E GUADAMUZ
• 金额: $ 13.83万
• 依托单位: MAHIDOL UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2016
• 资助国家: 美国
• 起止时间: 2016-02-08 至 2018-01-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/9064254
• 关键词: AIDS prevention; Anti-Retroviral Agents; Antibodies; Antigens; Asia; Behavior; Blood; Caring; Chemoprophylaxis; Clinic; Collection; Continuity of Patient Care; Counseling; Country; DNA; Data; Development; Diagnostic; Disease; Early identification; Epidemic; Feasibility Studies; Focus Groups; Funding Mechanisms; Future; HIV; HIV Infections; HIV Seropositivity; Human immunodeficiency virus test; Incidence; Infection; Internet; Interview; Investigation; Laboratories; Liquid substance; Maps; Methods; Modality; Nurses; Oral; Participant; Perception; Persons; Pilot Projects; Prevalence; Process; Professional counselor; Questionnaires; Reading; Recruitment Activity; Reporting; Research Project Grants; Research Proposals; Risk; Risk Reduction; Sampling; Services; Social Network; Spottings; Surveys; Target Populations; Technology; Testing; Thailand; Time; Training; Videoconferences; Videoconferencing; base; experience; follow-up; improved; innovation; insight; men who have sex with men; mobile application; prevent; prevention service; psychosocial; public health relevance; social; symposium; transmission process; uptake; web site; willingness; young men who have sex with men

 DESCRIPTION (provided by applicant): The HIV epidemic is accelerating among young men who have sex with men (YMSM, 18 to 24 years) in Bangkok where HIV incidence was reported to be 8.8 to 12.2 per 100 person-years, the highest such incidence documented in Asia. Engagement and retention of YMSM of unknown or HIV negative serostatus in regular (at least annual) HIV testing is essential for timely linkage to HIV prevention services, such as risk reduction counseling and HIV chemoprophylaxis. Among YMSM unaware of an existing or new HIV infection, timely identification is necessary to increase linkage and initiation of antiretrovial treatment and care to improve disease outlook and prevent onward HIV transmission. However, structural, logistical and psychosocial barriers limit the uptake and retention of Thai MSM in regular HIV testing, hindering the rollout of much needed HIV prevention and treatment services targeting this population. This study proposes the use of online HIV testing (OHT) as an alternative HIV testing modality to increase engagement, retention and linkage of YMSM in HIV prevention, treatment and care services. The specific aims of this research proposal are 1) To qualitatively explore barriers and facilitators to OHT among Bangkok YMSM; 2) To quantitatively examine current perceptions, barriers, facilitators to HIV testing among Bangkok YMSM and estimate the proportion likely to undergo OHT, identify factors associated with willingness to access OHT and to participate in a pilot study of this new HIV testing modality; and 3) To determine the acceptability and feasibility of OHT using a new HIV rapid diagnostic antibody/antigen-based self-test in real time and a self-collected dried blood spot (DBS) with centralized HIV DNA testing. Results of rapid testing will be read- and of centralized testing will be delivered by video conference, followed by discussion, post-test counseling and linkage to care and treatment, in a 6-month pilot study. Particularly, logistical issues, concerns over rapid HIV self-testing, DBS self-collection and laboratory testing, reading or reporting of results by video conferencing will be assessed, as well as how OHT may help to overcome some of the existing barriers to HIV testing. Using new HIV diagnostic and online technologies, OHT may be a promising strategy to increase engagement, retention and linkage to HIV prevention, treatment and care services among Thai YMSM.

 描述（由申请人提供）：艾滋病毒在曼谷男男性行为者（YMSM，18 至 24 岁）中的流行正在加速，据报告，艾滋病毒发病率为每 100 人年 8.8 至 12.2 例，是亚洲记录的最高发病率。在定期（至少每年一次）HIV 检测中参与和保留未知或 HIV 阴性血清状态的 YMSM 对于及时联系 HIV 预防服务（例如降低风险咨询和 HIV 化学预防）至关重要。在不知道现有或新发艾滋病毒感染的 YMSM 中，有必要及时识别，以加强联系并启动抗逆转录病毒治疗和护理，以改善疾病前景并防止艾滋病毒继续传播。然而，结构性、后勤和社会心理障碍限制了泰国男男性行为者在定期艾滋病毒检测中的吸收和保留，阻碍了针对这一人群推出急需的艾滋病毒预防和治疗服务。本研究建议使用在线 HIV 检测 (OHT) 作为替代 HIV 检测方式，以提高 YMSM 在 HIV 预防、治疗和护理服务中的参与度、保留率和联系。本研究计划的具体目标是 1) 定性探索曼谷 YMSM 中 OHT 的障碍和促进因素； 2) 定量研究曼谷 YMSM 中目前对 HIV 检测的看法、障碍和促进因素，并估计可能接受 OHT 的比例，确定与接受 OHT 的意愿相关的因素以及参与这种新的 HIV 检测方式的试点研究； 3) 使用新型 HIV 快速诊断抗体/抗原实时自检和集中 HIV DNA 检测的自采集干血点 (DBS) 来确定 OHT 的可接受性和可行性。将读取快速测试的结果，并将读取集中测试的结果 在为期 6 个月的试点研究中，通过视频会议进行，随后进行讨论、测试后咨询以及与护理和治疗的联系。特别是后勤问题、对快速 HIV 自我检测、DBS 自我收集和实验室检测、通过视频会议读取或报告结果的担忧，以及 OHT 如何帮助克服 HIV 检测的一些现有障碍将得到评估。使用新的艾滋病毒诊断和在线技术，OHT 可能是一项有前途的战略，可以提高泰国 YMSM 中艾滋病毒预防、治疗和护理服务的参与度、保留率和联系。