HIV self-testing with online supervision for Vietnamese MSM

越南男男性行为者艾滋病毒自我检测和在线监督

• 批准号: 10471788
• 负责人: THOMAS E GUADAMUZ
• 金额: $ 15.36万
• 依托单位: MAHIDOL UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2021
• 资助国家: 美国
• 起止时间: 2021-08-19 至 2024-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10471788
• 关键词: AIDS prevention; Antigens; Asia; Awareness; Behavioral; Blood; Bypass; Caring; Cellular Phone; Chemoprophylaxis; Cities; Clip; Collaborations; Collection; Communities; Continuity of Patient Care; Counseling; DNA; Data; Diagnostic; Diagnostic Reagent Kits; Disease; Early Diagnosis; Enrollment; Epidemic; Epidemiology; Event; Feasibility Studies; Focus Groups; Funding Mechanisms; HIV; HIV Infections; HIV Seronegativity; Health; Human immunodeficiency virus test; Incidence; Individual; Internet; Intervention; Knowledge; Laboratories; Logistics; Measures; Modality; Molecular Epidemiology; Outcome; Persons; Pilot Projects; Population; Pre-Post Tests; Prevalence; Professional counselor; Rapid diagnostics; Reading; Reporting; Research; Research Personnel; Research Proposals; Resources; Risk; Risk Reduction; Sexual Partners; Social Network; Spottings; Supervision; Surveys; Target Populations; Technology; Testing; Thailand; Time; Translations; Universities; Unsafe Sex; Videoconferencing; Vietnam; Virus; acceptability and feasibility; antibody diagnostic; antiretroviral therapy; base; behavioral outcome; care systems; design; experience; improved; interest; men who have sex with men; novel strategies; pilot test; prevent; prevention service; psychosocial; rapid testing; recruit; self testing; social culture; social stigma; standard of care; transmission process; treatment services; uptake; video delivery; virtual; willingness; young men who have sex with men

PROJECT SUMMARY/ABSTRACT There is a concentrated HIV epidemic among young men who have sex with men in Vietnam where HIV incidence was reported to be 5.8 per 100 person-years, one of the highest incidences in the region. Regular (at least annual) HIV testing of YMSM of unknown or HIV negative serostatus is critical for timely linkage to HIV prevention services, such as risk reduction counseling and HIV chemoprophylaxis. Among YMSM unaware of an existing or new HIV infection, timely identification is necessary to increase linkage and initiation of antiretroviral treatment and care to improve disease outlook and prevent onward HIV transmission. However, structural, logistical and psychosocial barriers limit the uptake and retention of Vietnamese MSM in regular HIV testing, hindering the rollout of much needed HIV prevention and treatment services targeting this population. This study proposes the use of online HIV testing (OHT) as an alternative HIV testing modality to increase engagement, retention and linkage of YMSM in HIV prevention, treatment and care services. The specific aims of this research proposal are 1) To identify potential barriers and facilitators to uptake of OHT among YMSM; 2) to develop an empirical profile of barriers and facilitators to HIV testing among YMSM, including an estimate of the proportion of YMSM likely to participate in an OHT intervention; and 3) To conduct a preliminary assessment of the OHT intervention, including introduction of a new HIV rapid diagnostic antibody/antigen-based self-testing with an HIV counselor through video conferencing, and “real time” self-collected dried blood spot (DBS) technology with centralized HIV DNA testing. Results of rapid testing will be read- and of centralized testing will be delivered by video conference, followed by discussion, post-test counseling and linkage to care and treatment, in a 12-month pilot study. Particularly, logistical issues, concerns over rapid HIV self-testing, DBS self-collection and laboratory testing, reading or reporting of results by video conferencing will be assessed, as well as how OHT may help to overcome some of the existing barriers to venue-based HIV testing. Using new HIV diagnostic and online technologies, OHT may be a promising strategy to increase engagement, retention and linkage to HIV prevention, treatment and care services among Vietnamese YMSM.

项目总结/摘要 在越南，艾滋病集中在与男性发生性关系的年轻男子中 据报道，艾滋病毒的发病率为每100人年5.8人，是世界上最高的 该地区的事件。定期（至少每年一次）对未知的YMSM或HIV进行HIV检测 阴性血清状态对于及时与艾滋病毒预防服务联系至关重要， 减少咨询和艾滋病毒化学预防。在YMSM不知道现有或 新的艾滋病毒感染，及时识别是必要的，以增加联系和启动 抗逆转录病毒治疗和护理，以改善疾病前景并预防艾滋病毒传播 传输然而，结构性、后勤和心理社会障碍限制了人们的接受， 越南男男性接触者在定期艾滋病毒检测中的保留，阻碍了急需的 针对这一人群的艾滋病毒预防和治疗服务。本研究建议使用 将在线艾滋病毒检测（OHT）作为一种替代艾滋病毒检测方式，以提高参与度， 在艾滋病毒预防、治疗和护理服务中保留青年男男性接触者并将其与之挂钩。具体 本研究建议的目的是：1）确定吸收的潜在障碍和促进因素 2）建立艾滋病毒的障碍和促进因素的经验概况 在YMSM中进行测试，包括估计YMSM可能参与的比例 OHT干预;以及3）对OHT进行初步评估 干预措施，包括采用新的艾滋病毒快速诊断抗体/抗原 通过视频会议与艾滋病毒咨询师进行自我检测，并“真实的时间”自我收集 干血斑（DBS）技术与集中的艾滋病毒DNA检测。快速检测结果 将通过视频会议进行集中测试，然后 讨论、测试后咨询以及与护理和治疗的联系，为期12个月的试点 study.特别是后勤问题，对快速艾滋病毒自我检测、DBS自我采集的担忧 和实验室测试，阅读或通过视频会议报告结果将是 评估，以及OHT如何帮助克服一些现有的障碍， 基于场所的艾滋病毒检测。使用新的艾滋病毒诊断和在线技术，OHT可能是一种 加强参与、留用和与艾滋病毒预防的联系的有希望的战略， 越南YMSM的治疗和护理服务。