IGF::OT::IGF PLATFORM FOR NEUROCOGNITIVE EVALUATION AND MONITORING

IGF::OT::IGF 神经认知评估和监测平台

• 批准号: 9362105
• 负责人: DUANE JUNG
• 金额: $ 22.49万
• 依托单位: VIRIDIAN TECHNOLOGIES, INC.
• 依托单位国家: 美国
• 财政年份: 2016
• 资助国家: 美国
• 起止时间: 2016-09-19 至 2017-06-18
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/9362105
• 关键词: Architecture; Attention; Clinical Research; Cognitive; Cognitive Science; Computer software; Contracts; Data; Data Analyses; Development; Disease; Educational workshop; Evaluation; Impaired cognition; Injury; Institutional Review Boards; Legal; Malignant Neoplasms; Memorial Sloan-Kettering Cancer Center; Methods; Monitor; Motor; Neurocognitive; Neuropsychological Tests; Neurosciences Research; Paper; Participant; Phase; Privacy; Recovery; Recruitment Activity; Reporting; Research Design; Research Infrastructure; Secure; Sensitivity and Specificity; Short-Term Memory; Small Business Innovation Research Grant; Specificity; Testing; Training; Treatment-Related Cancer; Visuospatial; base; built environment; cognitive change; cognitive neuroscience; cognitive testing; cost; data visualization; database structure; design; executive function; experience; processing speed; prototype; theories; usability

Current standardized neuropsychological tests are based on decades‐old paper and pencil methods. They lack reliability, sensitivity, specificity, repeatability, and require trained neuropsychologists to administer them. Their administration in clinical and research settings result in high cost, complexity, and inconsistent results. There is a need and a commercial opportunity for an extensible cognitive assessment platform based on contemporary cognitive psychology and neuroscience research that can remotely, repeatedly, and reliably detect subtle and cognitive impairments and changes that can occur as a result of disease, disease treatment, and injury progression and recovery. This Phase I SBIR project will research, design, prototype, and assess the feasibility of a suite of cognitive assessments and a scalable, secure, privacy‐compliant software delivery, administration, scoring, data analysis, and data visualization platform that can repeatedly and reliably detect subtle cognitive impairments and changes that can occur as a result of cancer or cancer related treatments. These assessments will be brief, tolerable, reliable, sensitive with specificity, remotely administered, game like with an enriched user experience, and will be based on advances in neuroscientific theory. The suite of assessments will cover cognitive domains including attention, executive function, working memory, verbal abilities, visuospatial ability, motor function, and processing speed.

目前的标准化神经心理学测试是基于几十年前的纸笔方法。它们缺乏可靠性、敏感性、特异性和可重复性，需要训练有素的神经心理学家来管理。 它们在临床和研究环境中的管理导致高成本、复杂性和不一致的结果。存在对基于当代认知心理学和神经科学研究的可扩展认知评估平台的需求和商业机会，所述可扩展认知评估平台可以远程地、重复地和可靠地检测由于疾病、疾病治疗以及损伤进展和恢复而可能发生的细微和认知障碍和变化。这个第一阶段SBIR项目将研究，设计，原型设计和评估一套认知评估和可扩展，安全，隐私兼容的软件交付，管理，评分，数据分析和数据可视化平台的可行性，可以重复和可靠地检测微妙的认知障碍和变化，可能会发生癌症或癌症相关治疗的结果。这些评估将是简短的，可容忍的，可靠的，敏感的特异性，远程管理，游戏般丰富的用户体验，并将基于神经科学理论的进步。这套评估将涵盖认知领域，包括注意力、执行功能、工作记忆、言语能力、视觉空间能力、运动功能和处理速度。