IGF::OT::IGF PLATFORM FOR NEUROCOGNITIVE EVALUATION AND MONITORING

目前的标准化神经心理测试是基于几十年前的纸和笔方法。它们缺乏可靠性、敏感性、特异性和可重复性，需要训练有素的神经心理学家来管理。它们在临床和研究环境中的管理导致了高昂的成本、复杂性和不一致的结果。存在对基于当代认知心理学和神经科学研究的可扩展认知评估平台的需求和商业机会，该平台可以远程、重复且可靠地检测由于疾病、疾病治疗以及损伤进展和康复而可能发生的细微和认知损伤和变化。这个第一阶段的SBIR项目将研究、设计、原型和评估一套认知评估的可行性，以及一个可扩展的、安全的、符合隐私规定的软件交付、管理、评分、数据分析和数据可视化平台，该平台可以反复可靠地检测癌症或癌症相关治疗可能导致的微小认知障碍和变化。这些评估将是简短的、可容忍的、可靠的、敏感的和特异性的、远程管理的、具有丰富用户体验的游戏式的，并将基于神经科学理论的进步。这套评估将涵盖认知领域，包括注意力、执行功能、工作记忆、语言能力、视觉空间能力、运动功能和处理速度。

Current standardized neuropsychological tests are based on decades‐old paper and pencil methods. They lack reliability, sensitivity, specificity, repeatability, and require trained neuropsychologists to administer them. Their administration in clinical and research settings result in high cost, complexity, and inconsistent results. There is a need and a commercial opportunity for an extensible cognitive assessment platform based on contemporary cognitive psychology and neuroscience research that can remotely, repeatedly, and reliably detect subtle and cognitive impairments and changes that can occur as a result of disease, disease treatment, and injury progression and recovery. This Phase I SBIR project will research, design, prototype, and assess the feasibility of a suite of cognitive assessments and a scalable, secure, privacy‐compliant software delivery, administration, scoring, data analysis, and data visualization platform that can repeatedly and reliably detect subtle cognitive impairments and changes that can occur as a result of cancer or cancer related treatments. These assessments will be brief, tolerable, reliable, sensitive with specificity, remotely administered, game like with an enriched user experience, and will be based on advances in neuroscientific theory. The suite of assessments will cover cognitive domains including attention, executive function, working memory, verbal abilities, visuospatial ability, motor function, and processing speed.