Retinal eye-tracking as a diagnostic tool for traumatic brain injury and concussion.

视网膜眼球追踪作为创伤性脑损伤和脑震荡的诊断工具。

• 批准号: 9315414
• 负责人: Christy Kathleen Sheehy
• 金额: $ 2.5万
• 依托单位: C. LIGHT TECHNOLOGIES, INC.
• 依托单位国家: 美国
• 财政年份: 2016
• 资助国家: 美国
• 起止时间: 2016-07-16 至 2017-02-28
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/9315414
• 关键词: Affect; Binocular Vision; Brain Concussion; California; Clinic; Clinical; Computer software; Craniocerebral Trauma; Diagnosis; Diagnostic; Doctor of Philosophy; Event; Eye; Eye Movements; Frequencies; Generations; Goals; Hour; Image; Institutes; Lasers; Light; Manufacturer Name; Marketing; Measurement; Measures; Mechanics; Monitor; Motion; Neurologic; Ophthalmoscopes; Optics; Optometry; Patient Monitoring; Patients; Performance; Protocols documentation; Pupil; Recovery; Research; Resolution; Retina; Retinal; Retinal Cone; Risk; Saccades; Scanning; Schedule; Sports; Sports Medicine; Staging; System; TBI Patients; Technology; Testing; Time; Traumatic Brain Injury; United States; Universities; Vision; base; design; instrument; nervous system disorder; novel; programs; public health relevance; rehabilitative care; sample fixation; screening; software development; student athlete; tool

 DESCRIPTION (provided by applicant): The goal of our project is to further develop the tracking scanning laser ophthalmoscope (TSLO) to enable widespread use of the technology for high-resolution eye-tracking for NCAA student-athletes with sports related head injuries, such as traumatic brain injury and concussions. Tracking is done via an image-based software program that monitors the image of the retina over time while simultaneously logging the displacements of the eye. Currently, this system is the most accurate, fast and functional eye-tracking system used in a standard ophthalmic instrument. The TSLO has the ability to non-invasively track the retina at 960 Hz, with an accuracy of 0.2 arcminutes or ~1 micron. This level of accuracy is unprecedented in the clinic and is crucial when monitoring minute changes in eye motion immediately after the time of impact and during post-concussion recovery. Current pupil eye-tracking technologies lack the sensitivity needed to accurately measure fixational eye movements (FEMs), an early stage indicator of many neurological disorders, with research grade eye-tracking systems being either far too invasive or costly to implement as diagnostic tools. The TSLO as a concussive screening tool would be the perfect fit for Sport Medicine Clinics and the locker room. Thus, there is a significant scientific and commercial opportunity for the improvement and expansion of the technical capabilities of the TSLO.

 描述（由申请人提供）：我们项目的目标是进一步开发跟踪扫描激光检眼镜 (TSLO)，以便能够广泛使用该技术对患有运动相关头部损伤（例如创伤性脑损伤和脑震荡）的 NCAA 学生运动员进行高分辨率眼动追踪。跟踪是通过基于图像的软件程序完成的，该程序随着时间的推移监控视网膜的图像，同时记录眼睛的位移。目前，该系统是标准眼科仪器中使用的最准确、最快速、最实用的眼动追踪系统。 TSLO 能够以 960 Hz 的频率无创地跟踪视网膜，精度为 0.2 弧分或约 1 微米。这种准确度在临床上是前所未有的，对于在撞击后立即监测眼球运动的微小变化以及脑震荡后恢复过程中至关重要。目前的瞳孔眼球追踪技术缺乏精确测量注视眼球运动（FEM）所需的灵敏度，这是许多神经系统疾病的早期指标，研究级眼球追踪系统作为诊断工具要么侵入性太大，要么成本高昂。 TSLO 作为震荡筛查工具非常适合运动医学诊所和更衣室。因此，这存在着重大的科学和商业机会。 TSLO 技术能力的改进和扩展。