Economic, health, and behavioral dimensions of HIV treatment scale-up

扩大艾滋病毒治疗的经济、健康和行为层面

• 批准号: 8847174
• 负责人: Jacob Bor
• 金额: $ 15.39万
• 依托单位: BOSTON UNIVERSITY MEDICAL CAMPUS
• 依托单位国家: 美国
• 财政年份: 2015
• 资助国家: 美国
• 起止时间: 2015-03-20 至 2019-01-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8847174
• 关键词: Address; Adult; Affect; Africa; African; Age; Area; Behavior; Belief; Caring; Cessation of life; Chronic Disease; Clinic; Cognitive; Collection; Communities; Complex; Consequences of HIV; Cost-Benefit Analysis; Costs and Benefits; Data; Data Analyses; Decision Making; Development; Dimensions; Disinhibition; Economics; Education; Effectiveness; Environment; Epidemiology; Evaluation; Exposure to; Focus Groups; Future; Goals; HIV; HIV Infections; HIV risk; Health; Health Benefit; Health Care Seeking Behavior; Health behavior; Human immunodeficiency virus test; Individual; Intervention; Interview; Investments; Lead; Life; Life Cycle Stages; Life Expectancy; Light; Longitudinal Surveys; Mentors; Methods; Modeling; Morbidity - disease rate; Patients; Perception; Play; Population; Population Study; Prevention; Productivity; Psychology; Public Sector; Qualitative Methods; Randomized; Reading; Research; Research Activity; Research Design; Research Personnel; Research Project Grants; Risk; Role; Rural; School Enrollments; Schools; Science; Services; Sex Behavior; Shapes; Site; South Africa; Surveys; Testing; Training; Training Activity; Wit; analytical tool; antiretroviral therapy; base; behavior influence; behavioral economics; behavioral health; brief intervention; care seeking; career; cohort; design; economic evaluation; economic outcome; efficacy trial; expectation; experience; follow-up; health economics; high risk sexual behavior; human capital; improved; informant; member; mortality; novel; population health; programs; public health relevance; scale up; school health; sex risk; skills; theories; transmission process; two-arm study; uptake; young adult

 DESCRIPTION: This proposed four-year development period will be used for research and training activities that will give Dr. Bor the skills and experience necessary to become an independent investigator. Dr. Bor's long-term career goal is to apply the theory and analytical tools of economics to the study of population health, with a focus on HIV treatment and prevention. Building on a strong background in quantitative data analysis, Dr. Bor has proposed a training plan to develop skills in mixed methods study designs, content area expertise in behavioral economics, and epidemiological approaches to causal inference. The training plan will involve formal coursework, directed readings on specific topics, and a mentored research project. The research will investigate how the scale-up of HIV treatment in rural South Africa has shaped beliefs about the HIV risk environment, and how these beliefs influence behaviors related to HIV testing, sexual behavior, and human capital investment (e.g., education). Although the health benefits of ART for HIV patients are well documented, less is known about how increased availability of ART has influenced economic, health, and care-seeking behaviors at the community level. These spillover effects have implications for cost-benefit analyses of ART scale-up, and may inform interventions to increase HIV testing, care, and treatment. The proposed research will combine analysis of existing data from a health and demographic surveillance site in rural KwaZulu-Natal with collection of primary qualitative, survey, and experimental data in a mixed methods design. A brief intervention to increase take up of HIV testing will be developed and piloted in a randomized evaluation.

 描述：拟议的四年开发期将用于研究和培训活动，这些活动将使 Bor 博士获得成为独立研究者所需的技能和经验。博尔博士的长期职业目标是将经济学理论和分析工具应用于人口健康研究，重点是艾滋病毒治疗和预防。博尔博士凭借在定量数据分析方面的强大背景，提出了一项培训计划，以培养混合方法研究设计、行为经济学内容领域专业知识以及因果推理的流行病学方法方面的技能。培训计划将包括正式课程、特定主题的定向阅读和指导研究项目。该研究将调查南非农村地区艾滋病毒治疗的扩大如何塑造了人们对艾滋病毒风险环境的信念，以及这些信念如何影响与艾滋病毒检测、性行为和人力资本投资（例如教育）相关的行为。尽管抗逆转录病毒治疗对艾滋病毒患者的健康益处已有充分记录，但人们对抗逆转录病毒治疗的可用性的增加如何影响社区层面的经济、健康和就医行为知之甚少。这些溢出效应对扩大抗逆转录病毒治疗的成本效益分析具有影响，并可能为增加艾滋病毒检测、护理和治疗的干预措施提供信息。拟议的研究将对夸祖鲁-纳塔尔省农村地区健康和人口监测点的现有数据进行分析，并以混合方法设计收集主要定性、调查和实验数据。将制定一项旨在提高艾滋病毒检测率的简短干预措施，并在随机评估中进行试点。