User-Centered, Web-based Portal to Support Regimen Adherence in Transplant

描述（由申请人提供）：药物依从性是器官移植受者面临的主要挑战，也是肾和肝移植受者移植失败的主要原因。此外，在初级保健患者中进行的研究发现，健康素养是药物依从性的一个重要风险因素，使用简单易懂的药物信息可以提高药物依从性。到目前为止，改善实体器官移植受者药物自我管理的干预措施取得的成功有限。该提案将建立在初级保健中许多个体干预组件的大量证据基础上，以开发一个多方面的门户网站，该门户网站将作为未来多组分干预的关键基础设施，以帮助新的器官移植接受者进行自我护理并管理与医疗保健提供者的沟通。我们将开发一个以用户为中心的通信工具，该工具将利用电子医疗记录和常见技术（网站，短信）来提高移植受者的药物依从性。我们将采用以社区为基础的参与式研究方法，设计和开发基于网络的移植患者门户网站的原型，以帮助新的移植受者参与其复杂药物治疗方案的自我管理。

DESCRIPTION (provided by applicant): Medication adherence is a major challenge among organ transplant recipients, and is the leading cause of graft failure among kidney and liver transplant recipients. Furthermore, studies among primary care patients have found that health literacy is an important risk factor for medication adherence, and that the use of simple, plain-language medication information can improve medication adherence. Thus far, interventions to improve medication self-management among solid organ transplant recipients have had limited success. This proposal will build upon a substantial evidence base of many individual intervention components in primary care to develop a multifaceted web portal that will serve as key infrastructure for a future, multicomponent intervention to help new organ transplant recipients engage in self-care and manage communications with health care providers. We will develop a user-centered communications tool that will leverage electronic healthcare records and common technologies (website, SMS text) to improve medication adherence among transplant recipients. We will use a community-based participatory research approach to design and develop the prototype of a web-based Transplant Patient Portal to help new transplant recipients engage in self- management of their complex medication regimens.