Neurophysiology of Weakness and Exercise in Rotator Cuff Tendinopathy

描述(由申请人提供)：我们研究议程的长期目标是确定与肩袖肌腱病(撞击综合征)相关的机制，并随后评估针对这些机制的新治疗策略。这项应用的目的是研究肩袖肌腱病患者的肌肉模式，以及疼痛和运动对这些模式的影响。我们的第一个假设是，肩部注射的疼痛缓解将导致肩袖活动增加。我们的第二个假设是，肌腱病患者在六周的锻炼计划后将表现出肩袖肌肉活动的改善，而且这种改善在对治疗反应良好的患者中会更高。我们的最后一个假设是，与健康受试者相比，肩袖肌腱病患者的肩袖活动度会降低。我们计划使用几种用于肌肉活动评估的新技术来解决这些假设。

DESCRIPTION (provided by applicant): The long-term goal of our research agenda is to identify the mechanisms associated with rotator cuff tendinopathy (impingement syndrome) and subsequently evaluate novel treatment strategies that address these mechanisms. The objectives of this application are to study the muscle patterns in patients with rotator cuff tendinopathy as well as the effects of both pain and exercise on these patterns. Our first hypothesis is that pain relief from a shoulder injection will result in increased rotator cuff actiity. Our second hypothesis is that patients with tendinopathy will demonstrate improved rotator cuff muscle activity following a six-week exercise program and that this improvement will be higher in patients that respond favorably to treatment. Our final hypothesis is that patients with cuff tendinopathy will show decreased rotator cuff activity compared to healthy subjects. We plan on addressing these hypotheses using several novel techniques for muscle activity assessment.