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中文摘要
翻译
 描述(由申请人提供):这是美国心脏协会(AHA)基础心血管科学(BCVS)2015年夏季年度研讨会的新申请。这次会议在过去10年里得到了NHLBI的持续支持,这次会议将是11周年纪念会议。来自NHLBI的支持帮助促成了一次会议,该会议已成为处理分子心血管生物学和疾病的“去”会议。它代表其赞助商,美国心脏协会的BCVS,这是世界领先的心血管科学家组织。这个会议最初开始于二十年前,当时理事会于1991年举行了一次分子心脏病学会议,然后举行了几次会议,最初被称为雪鸟会议,因为它是在夏天在犹他州的雪鸟举行的。该会议于2002年成为年度活动,自2004年以来,该会议已被公认为AHA的永久性,经常性的科学会议,这是R13资助也开始的时候。近年来的会议增加了翻译主题以及本次会议的“面包和黄油”,这是基础分子心血管研究。该会议一直吸引着microRNA、心脏基因和细胞治疗、心脏发育以及最近的组织工程和iPS细胞等领域的领先研究人员。这个会议的出席人数每年都在攀升,2014年我们有超过600人的历史最高出席人数。与往年一样,会议将于7月举行,今年将在拉斯维加斯举行两年后回到新奥尔良(2011年和2012年会议的地点)。会议将在路易斯安那州新奥尔良市新奥尔良滨江的希尔顿酒店举行。计划的议程代表了一个雄心勃勃的,快节奏的会议,在4天内(2015年7月13日至16日)举行了14次会议,包括Eric Olson博士的主题演讲。年轻的心血管科学家也将通过每场会议的特邀演讲得到强调,海报将在会议的3天内展示。这次会议的组织者是阿萨古斯塔夫松博士(加州大学圣地亚哥分校),安东尼罗森茨威格(贝丝以色列女执事医疗中心)和大卫J.莱弗(路易斯安那州立大学)。提案申请约占会议总预算的7%,正如我们在过去几年中所做的那样,该申请的支持将用于心血管外展奖(少数民族旅行奖)和青年研究者旅行奖。
英文摘要
 DESCRIPTION (provided by applicant): This is a new application for the Annual Summer 2015 Symposium of the Basic Cardiovascular Sciences (BCVS) of the American Heart Association (AHA). This conference has had continuous support from the NHLBI for the last 10 years and this will be the 11th Anniversary meeting. Support from the NHLBI has helped foster a meeting that has become the "go to" conference dealing with molecular cardiovascular biology and disease. It represents its sponsor, the BCVS of the AHA, which is the world's leading organization of cardiovascular scientists. This conference started originally two decades ago as the Council held a Molecular Cardiology conference in 1991 and then had several meetings initially hailed as the Snowbird Conference as it was held during the summer at Snowbird, Utah. The meeting became an annual event in 2002 and since 2004 this conference has been recognized as a permanent, recurring scientific meeting of the AHA and which is when R13 funding also commenced. The conference in recent years has added translational topics as well as the "bread and butter" of this meeting, which is basic molecular cardiovascular research. The conference has always attracted the leading researchers in fields such as microRNA, cardiac gene and cell therapy, cardiac development and most recently, tissue engineering and iPS cells. The attendance of this conference has climbed every year and in 2014 we had an all-time high attendance of over 600. As in past years, the conference will be held in July and this year will return to New Orleans (the site of the 2011 and 2012 meetings) after two years in Las Vegas. The meeting will be held at the Hilton New Orleans Riverside, New Orleans, LA. The planned agenda represents an ambitious, fast-paced meeting with 14 sessions over 4 days (July 13-16, 2015) including the Keynote lecture by Dr. Eric Olson. Young cardiovascular scientists will be highlighted as well through invited talks in each session and Posters will be presented over the course of 3 days of the conference. Organizers of this meeting are Drs. Asa Gustafsson (UCSD), Anthony Rosenzweig (Beth Israel Deaconess Medical Center) and David J. Lefer (Louisiana State University). The proposal request constitutes approximately 7% of the total meeting budget and as we have done over the last several years, support from this application will be used toward Cardiovascular Outreach Awards (minority travel awards) and Young Investigator Travel Awards.
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Full-scale GMP Production for a Pre-Clinical Systemic Delivered Mesenchymal Stem Cells Derived Extracellular Vesicles For Cardiovascular Disease
1/2 Allogeneic Human Mesenchymal Stem Cell (MSC) Injection in Patients with Hypoplastic Left Heart Syndrome: A Phase IIb Clinical Trial
1/2 Allogeneic Human Mesenchymal Stem Cell (MSC) Injection in Patients with Hypoplastic Left Heart Syndrome: A Phase IIb Clinical Trial
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