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Patient tailored anti-tumour T cells to prevent relapse in patients with acute myeloid leukaemia undergoing allogeneic haemopoietic stem cell transplantation

Patient tailored anti-tumour T cells to prevent relapse in patients with acute myeloid leukaemia undergoing allogeneic haemopoietic stem cell transplantation
为患者量身定制抗肿瘤T细胞,以预防接受同种异体造血干细胞移植的急性髓系白血病患者复发
批准号:
nhmrc : 1089398
负责人:
Dr Emily Blyth
金额:
$12.7万
依托单位国家:
澳大利亚
项目类别:
Early Career Fellowships
财政年份:
2015
资助国家:
澳大利亚
项目状态:
已结题
起止时间:
2015-01-01 至 2018-12-31

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项目成果

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中文摘要
翻译
急性髓系白血病(AML)是成人最常见的急性白血病。高危AML患者的两年存活率不到20%。健康捐献者的血液或骨髓移植通常是治愈的唯一机会,但白血病经常复发。Blyth博士将进行一项临床试验,将来自移植捐赠者的抗白血病免疫细胞用于高危AML患者,以防止移植后复发。
英文摘要
Acute myeloid leukaemia (AML) is the most common acute leukaemia in adults. Patients with high-risk AML have a 2-year survival of less than 20%. Blood or bone marrow transplant from a healthy donor is often the only chance of cure but the leukaemia frequently returns. Dr Blyth will perform a clinical trial giving leukaemia fighting immune cells from the transplant donor to patients with high risk AML to prevent relapse after transplant.
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A trial of tumour antigen targeted donor T cells in high risk acute myeloid leukaemia
  • 批准号:
    nhmrc : GNT1088118
  • 项目类别:
    Project Grants
  • 资助金额:
    $39.13万
  • 财政年份:
    2015
  • 负责人:
    Dr Emily Blyth
  • 依托单位:
Patient tailored anti-tumour T cells to prevent relapse in patients with acute myeloid leukaemia undergoing allogeneic haemopoietic stem cell transplantation
  • 批准号:
    nhmrc : GNT1089398
  • 项目类别:
    Early Career Fellowships
  • 资助金额:
    $18.47万
  • 财政年份:
    2015
  • 负责人:
    Dr Emily Blyth
  • 依托单位:
A trial of tumour antigen targeted donor T cells in high risk acute myeloid leukaemia
  • 批准号:
    nhmrc : 1088118
  • 项目类别:
    Project Grants
  • 资助金额:
    $26.94万
  • 财政年份:
    2015
  • 负责人:
    Dr Emily Blyth
  • 依托单位:
海外基金