Engineering of antibody affinity and immunogenicity under the guidance of a computational model of B72.3/TAG72 complex
B72.3/TAG72 复合物计算模型指导下的抗体亲和力和免疫原性工程
基本信息
- 批准号:172730-2002
- 负责人:
- 金额:$ 2.19万
- 依托单位:
- 依托单位国家:加拿大
- 项目类别:Discovery Grants Program - Individual
- 财政年份:2003
- 资助国家:加拿大
- 起止时间:2003-01-01 至 2004-12-31
- 项目状态:已结题
- 来源:
- 关键词:
项目摘要
No summary - Aucun sommaire
无摘要- Aucun sommaire
项目成果
期刊论文数量(0)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
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Xiang, Jim其他文献
Th17 and Th17-stimulated CD8+ T cells play a distinct role in Th17-induced preventive and therapeutic antitumor immunity
- DOI:
10.1007/s00262-011-1054-y - 发表时间:
2011-10-01 - 期刊:
- 影响因子:5.8
- 作者:
Munegowda, Manjunatha Ankathatti;Deng, Yulin;Xiang, Jim - 通讯作者:
Xiang, Jim
Heterologous human/rat HER2-specific exosome-targeted T cell vaccine stimulates potent humoral and CTL responses leading to enhanced circumvention of HER2 tolerance in double transgenic HLA-A2/HER2 mice
- DOI:
10.1016/j.vaccine.2018.01.078 - 发表时间:
2018-03-07 - 期刊:
- 影响因子:5.5
- 作者:
Xie, Yufeng;Wu, Jie;Xiang, Jim - 通讯作者:
Xiang, Jim
Novel exosome-targeted T-cell-based vaccine counteracts T-cell anergy and converts CTL exhaustion in chronic infection via CD40L signaling through the mTORC1 pathway
- DOI:
10.1038/cmi.2016.23 - 发表时间:
2017-06-01 - 期刊:
- 影响因子:24.1
- 作者:
Wang, Rong;Xu, Aizhang;Xiang, Jim - 通讯作者:
Xiang, Jim
Nonspecific CD4+ T cells with uptake of antigen-specific dendritic cell-released exosomes stimulate antigen-specific CD8+ CTL responses and long-term T cell memory
- DOI:
10.1189/jlb.0407249 - 发表时间:
2007-10-01 - 期刊:
- 影响因子:5.5
- 作者:
Hao, Siguo;Yuan, Jinying;Xiang, Jim - 通讯作者:
Xiang, Jim
Post hoc analysis of a randomized, double-blind, placebo-controlled efficacy and tolerability study of tramadol extended release for the treatment of osteoarthritis pain in geriatric patients
- DOI:
10.1016/j.clinthera.2007.12.009 - 发表时间:
2007-01-01 - 期刊:
- 影响因子:3.2
- 作者:
Vorsanger, Gary;Xiang, Jim;Farrell, Jean - 通讯作者:
Farrell, Jean
Xiang, Jim的其他文献
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{{ truncateString('Xiang, Jim', 18)}}的其他基金
Simulated microgravity blocks osteoblastic differentiation and mineralization leading to bone loss via suppressing the FAK/RhoA-regulated Wnt pathway
模拟微重力通过抑制 FAK/RhoA 调节的 Wnt 通路来阻止成骨细胞分化和矿化,从而导致骨质流失
- 批准号:
RGPIN-2019-03980 - 财政年份:2022
- 资助金额:
$ 2.19万 - 项目类别:
Discovery Grants Program - Individual
Simulated microgravity blocks osteoblastic differentiation and mineralization leading to bone loss via suppressing the FAK/RhoA-regulated Wnt pathway
模拟微重力通过抑制 FAK/RhoA 调节的 Wnt 通路来阻止成骨细胞分化和矿化,从而导致骨质流失
- 批准号:
RGPIN-2019-03980 - 财政年份:2021
- 资助金额:
$ 2.19万 - 项目类别:
Discovery Grants Program - Individual
Simulated microgravity blocks osteoblastic differentiation and mineralization leading to bone loss via suppressing the FAK/RhoA-regulated Wnt pathway
模拟微重力通过抑制 FAK/RhoA 调节的 Wnt 通路来阻止成骨细胞分化和矿化,从而导致骨质流失
- 批准号:
RGPIN-2019-03980 - 财政年份:2020
- 资助金额:
$ 2.19万 - 项目类别:
Discovery Grants Program - Individual
Simulated microgravity blocks osteoblastic differentiation and mineralization leading to bone loss via suppressing the FAK/RhoA-regulated Wnt pathway
模拟微重力通过抑制 FAK/RhoA 调节的 Wnt 通路来阻止成骨细胞分化和矿化,从而导致骨质流失
- 批准号:
RGPIN-2019-03980 - 财政年份:2019
- 资助金额:
$ 2.19万 - 项目类别:
Discovery Grants Program - Individual
Structure/functional analysis of phage display-derived and molecularly designed loop peptides with high binding affinity for human tumor-specific NeuAc2-6aGal-NAcal-O-Ser
对噬菌体展示衍生的和分子设计的环肽进行结构/功能分析,该环肽对人类肿瘤特异性 NeuAc2-6aGal-NAcal-O-Ser 具有高结合亲和力
- 批准号:
298929-2004 - 财政年份:2006
- 资助金额:
$ 2.19万 - 项目类别:
Collaborative Health Research Projects
Engineering of antibody affinity and immunogenicity under the guidance of a computational model of B72.3/TAG72 complex
B72.3/TAG72 复合物计算模型指导下的抗体亲和力和免疫原性工程
- 批准号:
172730-2002 - 财政年份:2006
- 资助金额:
$ 2.19万 - 项目类别:
Discovery Grants Program - Individual
Structure/functional analysis of phage display-derived and molecularly designed loop peptides with high binding affinity for human tumor-specific NeuAc2-6aGal-NAcal-O-Ser
对噬菌体展示衍生的和分子设计的环肽进行结构/功能分析,该环肽对人类肿瘤特异性 NeuAc2-6aGal-NAcal-O-Ser 具有高结合亲和力
- 批准号:
298929-2004 - 财政年份:2005
- 资助金额:
$ 2.19万 - 项目类别:
Collaborative Health Research Projects
Engineering of antibody affinity and immunogenicity under the guidance of a computational model of B72.3/TAG72 complex
B72.3/TAG72 复合物计算模型指导下的抗体亲和力和免疫原性工程
- 批准号:
172730-2002 - 财政年份:2005
- 资助金额:
$ 2.19万 - 项目类别:
Discovery Grants Program - Individual
Engineering of antibody affinity and immunogenicity under the guidance of a computational model of B72.3/TAG72 complex
B72.3/TAG72 复合物计算模型指导下的抗体亲和力和免疫原性工程
- 批准号:
172730-2002 - 财政年份:2004
- 资助金额:
$ 2.19万 - 项目类别:
Discovery Grants Program - Individual
Structure/functional analysis of phage display-derived and molecularly designed loop peptides with high binding affinity for human tumor-specific NeuAc2-6aGal-NAcal-O-Ser
对噬菌体展示衍生的和分子设计的环肽进行结构/功能分析,该环肽对人类肿瘤特异性 NeuAc2-6aGal-NAcal-O-Ser 具有高结合亲和力
- 批准号:
298929-2004 - 财政年份:2004
- 资助金额:
$ 2.19万 - 项目类别:
Collaborative Health Research Projects
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CD8+T细胞亚群在抗MDA5抗体阳性皮肌炎中的致病机制研究
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