Phase III Trial of Radical Chemo-radiation Vs Radiation alone in the management of localised Bladder TCC.

这项试验旨在观察化疗和放疗的联合治疗在根除肿瘤和保留膀胱方面是否确实上级单纯放疗。如果这项研究的最终结果确实显示放化疗明显上级单纯放疗，而不增加发病率，（特别是长期副作用），这可能为更大比例的局部膀胱癌患者奠定平台，首先考虑的是这个机构（膀胱）保留方法，这已经成为现实，在许多其他部位的癌症与使用多模态治疗。

This trial aims to see if the combination of Chemotherapy and Radiation treatment is indeed superior in eradicating the tumor and preserving the Bladder in a greater number of patients as compared to Radiation treatment alone. If the final results from this study do show chemoradiotherapy to be significantly superior to radiation alone, without an increase in morbidity ( especially long term side effects ) , this may lay the platform for a greater proportion of patients with localised bladder cancer, being in the first instance considered for this organ( bladder) preserving approach something which has become a reality at a number of other sites of cancer with the use of multimodality treatment.