Preservation and generation of beta cells in type 1 diabetes with novel mimetic peptides

用新型模拟肽保存和生成 1 型糖尿病中的 β 细胞

• 批准号: nhmrc : 2004064
• 金额: $ 109.61万
• 依托单位国家: 澳大利亚
• 项目类别: Ideas Grants
• 财政年份: 2021
• 资助国家: 澳大利亚
• 起止时间: 2021-01-01 至 2024-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/preservation-generation-beta-mimetic-peptides/1780275
• 关键词: Preservation; generation; beta; cells; type

Type 1 diabetes (T1D) is an autoimmune disease that destroys insulin producing beta cells in the pancreas. It can cause heart and kidney disease, and nerve damage. T1D is treated with insulin injections that can cause life-threatening low blood sugar levels. We have developed a new treatment that may stop beta cell loss, generate new beta cells and remove the need for insulin injections in T1D patients. A positive outcome will identify a completely new T1D treatment option.

1型糖尿病（T1D）是一种自身免疫性疾病，它破坏胰腺中产生胰岛素的β细胞。它会导致心脏和肾脏疾病，以及神经损伤。T1D通过胰岛素注射治疗，可导致危及生命的低血糖水平。我们已经开发出一种新的治疗方法，可以阻止β细胞丢失，产生新的β细胞，并消除T1D患者对胰岛素注射的需求。积极的结果将确定一个全新的T1D治疗选择。