Preventing early-onset pneumonia in Indigenous infants through maternal immunisation: a multi-centre randomised controlled trial

通过母亲免疫预防土著婴儿早发性肺炎：一项多中心随机对照试验

• 批准号: nhmrc : GNT1138555
• 负责人: A/Pr Geeta Swamy
• 金额: $ 321.06万
• 依托单位国家: 澳大利亚
• 项目类别: Project Grants
• 财政年份: 2018
• 资助国家: 澳大利亚
• 起止时间: 2018-01-01 至 无数据
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/preventing-early-onset-controlled-trial/1348157
• 关键词: Preventing; early; onset; pneumonia; Indigenous

We plan a study where Indigenous pregnant women will be immunised with a licensed vaccine to determine if it prevents acute lung infections in their children. A randomised design will be used based on our previous work. We will also undertake 2 novel sub-studies on infant immune function and reasons why women refuse immunisation. If successful, this study will alter immunisation policy and prevent lung infections and future chronic lung diseases that are common in Indigenous children and adults.

我们计划进行一项研究，土著孕妇将接种一种许可的疫苗，以确定它是否能预防其子女的急性肺部感染。基于我们以前的工作，将使用随机设计。我们还将开展2项关于婴儿免疫功能和女性拒绝免疫接种原因的新子研究。如果成功，这项研究将改变免疫政策，预防肺部感染和未来的慢性肺部疾病，这些疾病在土著儿童和成人中很常见。