Prevention and Treatment of Chronic Heart and Kidney Disease via Epidemiological, Pharmacol Device and Cell-Based Approaches

通过流行病学、药物设备和细胞方法预防和治疗慢性心脏和肾脏疾病

• 批准号: nhmrc : 546272
• 负责人: Prof Christopher Reid
• 金额: $ 386.43万
• 依托单位: Monash University
• 依托单位国家: 澳大利亚
• 项目类别: Programs
• 财政年份: 2009
• 资助国家: 澳大利亚
• 起止时间: 2009-01-01 至 2014-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/prevention-treatment-chronic-based-approaches/100540
• 关键词: Prevention; Treatment; Chronic; Heart; Kidney

Heart failure describes where the heart cannot pump adequately to meet the needs of the body. This condition has a high mortality despite recent advances in therapy, therefore, there is an urgent need for new approaches to this condition. The present grant aims to: (1) identify patients at high-risk for future development of this condition where early intervention with drugs may reduce or prevent the development of new heart failure; (2) use novel drugs, devices and stem cell therapies to identify ways to better treat patients with existing disease; (3) focus on the effect of heart failure on the kidney and vice versa via early diagnosis and treatment strategies

心力衰竭是指心脏无法充分泵血以满足身体的需要。尽管治疗方法最近取得了进展，但这种情况的死亡率很高，因此，迫切需要针对这种情况的新方法。目前的赠款旨在：（1）识别未来发生这种情况的高风险患者，早期药物干预可能会减少或预防新的心力衰竭的发生； (2) 使用新药物、设备和干细胞疗法来确定更好地治疗现有疾病患者的方法； (3)关注心力衰竭对肾脏的影响以及肾脏对心力衰竭的影响，早期诊断和治疗策略