Understanding the neuronal mechanisms underlying inherited epilepsies

了解遗传性癫痫的神经机制

• 批准号: FT0990628
• 负责人: Prof Christopher Reid
• 金额: $ 46.96万
• 依托单位: The Florey Institute of Neuroscience and Mental Health
• 依托单位国家: 澳大利亚
• 项目类别: ARC Future Fellowships
• 财政年份: 2010
• 资助国家: 澳大利亚
• 起止时间: 2010-01-04 至 2014-01-03
• 项目状态: 已结题
• 来源: https://dataportal.arc.gov.au/RGS/Web/Grants/FT0990628
• 关键词: Understanding; neuronal; mechanisms; underlying; inherited

Epilepsy is a serious disease that impacts severely on individuals and the community as a whole. Conservative estimates suggest a financial cost of more than $2 billion per annum. Drug treatment for this disease is often not adequate. Recent advances have allowed scientists to determine mutation in human genes that cause epilepsy. New models of epilepsy based on this knowledge will allow us to better understand what causes epilepsy enabling us to devise new and potent therapeutic strategies to treat the disease.

癫痫是一种严重的疾病，严重影响个人和整个社会。据保守估计，每年的财政费用超过20亿美元。这种疾病的药物治疗往往是不够的。最近的进展使科学家能够确定导致癫痫的人类基因突变。 基于这些知识的癫痫新模型将使我们能够更好地了解癫痫的原因，使我们能够设计新的有效的治疗策略来治疗这种疾病。