Prospective Imaging Study of Ageing: Genes, Brain & Behaviour

衰老的前瞻性影像研究：基因、大脑

• 批准号: nhmrc : 1095227
• 负责人: A/Pr Gail Robinson
• 金额: $ 452.05万
• 依托单位: Queensland Institute of Medical Research
• 依托单位国家: 澳大利亚
• 项目类别: Targeted Calls
• 财政年份: 2015
• 资助国家: 澳大利亚
• 起止时间: 2015-01-01 至 2020-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/prospective-imaging-study-brain-behaviour/662355
• 关键词: Prospective; Imaging; Study; Ageing; Genes

While the burden of dementia in Australia occurs late in life, the underlying brain disease accumulates for decades prior to dementia onset. Disease modifying interventions have the greatest potential to avert later disease burden if introduced during this crucial window, well before the onset of clear cognitive decline. To reduce Australia's future dementia burden, it is thus imperative to identify those Australians at risk of dementia whilst they are still relatively young.

虽然在澳大利亚痴呆症的负担发生在生命的后期，但潜在的脑部疾病在痴呆症发作之前积累了数十年。如果在这一关键窗口期，即在明显的认知能力下降开始之前，疾病改善干预措施最有可能避免以后的疾病负担。因此，为了减少澳大利亚未来的痴呆症负担，必须在相对年轻的时候确定那些有痴呆症风险的澳大利亚人。