Radiotherapy vs chemotherapy for low-grade gliomas stratified for genetic 1p loss: efficacy and quality of life benefits

低度恶性神经胶质瘤是一种罕见的恶性脑肿瘤。手术、放疗和化疗可以延缓肿瘤的生长，但治愈是不常见的。目前，治疗的目标是尽可能长时间地控制肿瘤生长，同时保持生活质量。这项研究将放射治疗与一种新形式的化疗进行了比较，以了解哪种治疗方法最有效地控制肿瘤生长，产生的副作用最少，并导致更好的生活质量。

Low-grade glioma is an uncommon malignant brain tumour. Surgery, radiotherapy and chemotherapy delay growth of this tumour, but cure is uncommon. Currently the goal of treatment is to control tumour growth for as long as possible whilst maintaining quality of life. This study compares treatment with radiotherapy with a new form of chemotherapy to see which treatment controls tumour growth most effectively, which produces the least side effects and which results in the better quality of life.