Radiotherapy vs chemotherapy for low-grade gliomas stratified for genetic 1p loss: efficacy and quality of life benefits

低级别胶质瘤是一种罕见的恶性脑瘤。手术、放疗和化疗延缓了这种肿瘤的生长，但治愈并不常见。目前，治疗的目标是在保持生活质量的同时尽可能长时间地控制肿瘤的生长。这项研究比较了放射治疗和新形式的化疗，以确定哪种治疗方法最有效地控制肿瘤生长，哪种方法产生的副作用最少，哪种方法能带来更好的生活质量。

Low-grade glioma is an uncommon malignant brain tumour. Surgery, radiotherapy and chemotherapy delay growth of this tumour, but cure is uncommon. Currently the goal of treatment is to control tumour growth for as long as possible whilst maintaining quality of life. This study compares treatment with radiotherapy with a new form of chemotherapy to see which treatment controls tumour growth most effectively, which produces the least side effects and which results in the better quality of life.