REBALANCING THE LEVELS OF CCL17 AND CCL22 TO IMPROVE RHEUMATOID ARTHRITIS
REBALANCING THE LEVELS OF CCL17 AND CCL22 TO IMPROVE RHEUMATOID ARTHRITIS
批准号:
nhmrc : GNT1159901
负责人:
金额:
$65.17万
依托单位国家:
澳大利亚
项目类别:
Project Grants
财政年份:
2019
资助国家:
澳大利亚
项目状态:
已结题
起止时间:
2019-01-01 至 --
中文摘要
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英文摘要
Rheumatoid arthritis is the inflammatory disease's severest form, leading to poor quality of life. This study will investigate the expression and function of two chemokines, CCL17 and CCL22, in the development of arthritis. Using arthritis mouse models and patient samples, I will provide new understanding, not only of how these chemokines are regulated, but also of their role in mediating effector functions. I will comprehensively evaluate their suitability as treatment targets.
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