Reduction Of Chronic Post-surgical Pain with Ketamine - ROCKet Study

用氯胺酮减轻慢性术后疼痛 - ROCKet 研究

• 批准号: nhmrc : GNT1120848
• 负责人: A/Pr Lisbeth Evered
• 金额: $ 482.34万
• 依托单位国家: 澳大利亚
• 项目类别: Project Grants
• 财政年份: 2017
• 资助国家: 澳大利亚
• 起止时间: 2017-01-01 至 无数据
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/reduction-chronic-post-rocket-study/1347167
• 关键词: Reduction; Chronic; Post; surgical; Pain

Chronic post-surgical pain (CPSP) is a common complication of major surgery, and a significant burden on quality of life and ongoing health costs. Ketamine is a drug used by anaesthetists to treat severe acute surgical pain. Various small studies suggest that it may be unique in its ability to reduce the risk of CPSP. We propose a large trial of ketamine during & after anaesthesia for major surgery to test this. Demonstration of effectiveness would promote widespread change in clinical practice.

慢性术后疼痛（CPSP）是大手术的常见并发症，对生活质量和持续的健康费用造成重大负担。氯胺酮是麻醉师用来治疗严重急性手术疼痛的药物。各种小型研究表明，它在降低 CPSP 风险方面可能是独一无二的。我们建议在大型手术麻醉期间和麻醉后进行氯胺酮的大型试验来测试这一点。有效性的证明将促进临床实践的广泛变革。