An integrated “omic” approach to neurodevelopmental disorders using disease-discordant monozygotic twins
An integrated “omic” approach to neurodevelopmental disorders using disease-discordant monozygotic twins
使用疾病不一致的同卵双胞胎治疗神经发育障碍的综合“组学”方法
批准号：
nhmrc : GNT1114909
负责人：
Ms Namitha Mohandas
金额：
$8.48万
依托单位国家：
澳大利亚
项目类别：
Postgraduate Scholarships
财政年份：
2016
资助国家：
澳大利亚
项目状态：
已结题
起止时间：
2016-01-01 至 --
中文摘要
翻译
该项目针对自闭症谱系障碍、脑瘫和癫痫等神经发育障碍，重点研究影响这些障碍疾病机制的环境因素（表观遗传学）。该研究将对双胞胎样本进行，并将有助于在早期阶段诊断疾病风险。这也将有助于了解这些重要神经系统疾病的原因。
英文摘要
This project targets neurodevelopment disorders such as autism spectrum disorder, cerebral palsy and epilepsy and focuses on studying the environmental factors (epigenetics) affecting the disease mechanisms in these disorders. The study will be performed on twin samples and will help in the diagnosis of the disease risk at an earlier stage. It will also help to understand the causes of these important neurological diseases.
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