An investigation of the involvement of clotting factors in abdominal aortic aneurysm (AAA) progression within a mouse model

小鼠模型中凝血因子参与腹主动脉瘤 (AAA) 进展的研究

• 批准号: nhmrc : 1016349
• 负责人: Dr Sai Wang Seto
• 金额: $ 12.63万
• 依托单位: James Cook University
• 依托单位国家: 澳大利亚
• 项目类别: Early Career Fellowships
• 财政年份: 2011
• 资助国家: 澳大利亚
• 起止时间: 2011-01-01 至 2012-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/an-investigation-involvement-mouse-model/109767
• 关键词: investigation; involvement; clotting; factors; abdominal

Early stage weakening of the main abdominal artery is present in ~100,000 Australians and currently has no accepted therapy. Development of drug therapies which limit progression of the weakening process is urgently needed. In this study involvement of the clotting cascade in artery weakening will be investigated. The study have been planned in order to identify new strategies which can be developed as treatments for artery weakening in patients.

大约100，000名澳大利亚人存在腹部主动脉的早期弱化，目前尚无公认的治疗方法。迫切需要开发限制弱化过程进展的药物疗法。在这项研究中，将研究凝血级联反应在动脉弱化中的作用。该研究旨在确定可开发用于治疗患者动脉弱化的新策略。