An investigation of physiological adapatations contributing to weight regain after weight loss

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Why we gain weight, and why it s hard to maintain weight loss, is the focus of this study. We can regulate food intake by voluntary control in the short term ( dieting ), but our long term ability to control food intake is more complex. Many proteins work together to regulate food intake, as do circulating factors in our blood. Before and after weight loss, subjects feelings of hunger and satiety will be examined so that we can identify pathways that are involved in successful weight loss.