The awakening:GABA-A receptors as targets for improving motor function

觉醒：GABA-A 受体作为改善运动功能的靶标

• 批准号: nhmrc : 1124567
• 负责人: A/Pr Thomas Balle
• 金额: $ 50.16万
• 依托单位: Australian National University
• 依托单位国家: 澳大利亚
• 项目类别: Project Grants
• 财政年份: 2017
• 资助国家: 澳大利亚
• 起止时间: 2017-01-01 至 2019-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/awakeninggaba-a-receptors-motor-function/947386
• 关键词: awakening; GABA; receptors; targets; improving

Zolpidem (Stilnox) is a “sleeping pill” that is reported "awaken" people with severe motor, memory and speech disabilities that result from stroke or other brain injury. We have identified a novel target by which zolpidem can exert these effects. This project will characterise this target and assess drug effects in models of stroke.

唑吡坦（Stilnox）是一种“安眠药”，据报道，它可以“唤醒”因中风或其他脑损伤而导致严重运动、记忆和语言障碍的人。我们已经确定了一个新的目标，唑吡坦可以发挥这些作用。该项目将验证这一目标，并在中风模型中评估药物效果。