The central role of Connective Tissue Growth Factor in remodelling of asthmatic airways

结缔组织生长因子在哮喘气道重塑中的核心作用

• 批准号: nhmrc : 1061712
• 负责人: A/Pr Janette Burgess
• 金额: $ 45.94万
• 依托单位: Australian National University
• 依托单位国家: 澳大利亚
• 项目类别: Project Grants
• 财政年份: 2014
• 资助国家: 澳大利亚
• 起止时间: 2014-01-01 至 2018-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/central-role-connective-asthmatic-airways/454920
• 关键词: central; role; Connective; Tissue; Growth

In the asthmatic airway an increase in the number of blood vessels can affect an asthmatic's ability to breathe. We have recently found that growth factors which can promote vessel growth are increased in the airways of asthmatics. We want to understand how these growth factors act together to possibly control the blood vessels and how their behaviour is different in the asthmatic airways compared to the nonasthmatic airways.

在哮喘气道中，血管数量的增加会影响哮喘患者的呼吸能力。我们最近发现，生长因子，可以促进血管生长增加，在气道哮喘患者。我们想了解这些生长因子如何共同作用以控制血管，以及它们在哮喘气道中的行为与非哮喘气道相比有何不同。