The clinical significance of sex hormone crosstalk in estrogen receptor positive breast cancer.

雌激素受体阳性乳腺癌中性激素串扰的临床意义。

• 批准号: nhmrc : GNT1130077
• 负责人: A/Pr Elgene Lim
• 金额: $ 100.9万
• 依托单位国家: 澳大利亚
• 项目类别: Project Grants
• 财政年份: 2017
• 资助国家: 澳大利亚
• 起止时间: 2017-01-01 至 无数据
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/clinical-significance-sex-breast-cancer/1347790
• 关键词: clinical; significance; sex; hormone; crosstalk

Breast cancer is mainly a disease in which the sex hormone estrogen stimulates uncontrolled growth. We have recently discovered that other sex hormones, including progesterone and androgen, can redirect the actions of estrogen in breast cancers to halt growth or make a tumour disappear. This study will examine the complex interaction between all three sex hormones to develop new, more effective strategies for treating breast cancer.

乳腺癌主要是一种性激素雌激素刺激不受控制的生长的疾病。我们最近发现，其他性激素，包括黄体酮和雄激素，可以改变乳腺癌中雌激素的作用，使肿瘤停止生长或消失。这项研究将研究所有三种性激素之间的复杂相互作用，以开发新的，更有效的治疗乳腺癌的策略。