The complement cascade, cortical thinning and the development of psychosis

补体级联、皮质变薄和精神病的发展

• 批准号: nhmrc : GNT1159674
• 金额: $ 57.22万
• 依托单位国家: 澳大利亚
• 项目类别: Project Grants
• 财政年份: 2019
• 资助国家: 澳大利亚
• 起止时间: 2019-01-01 至 无数据
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/complement-cascade-cortical-development-psychosis/1379085
• 关键词: complement; cascade; cortical; thinning; development

Schizophrenia is a complex disorder with devastating consequences to those that experience it. Despite over a century of research we are still not clear what biological factors influence the disorder. This research will investigate the role of a specific component of the immune system, called complement proteins, in the blood and brain of schizophrenia patients and how they impact patient outcomes. This research will improve our understanding of the biological factors involved in schizophrenia.

精神分裂症是一种复杂的疾病，对那些经历它的人来说是毁灭性的后果。尽管经过了世纪的研究，我们仍然不清楚是什么生物因素影响了这种疾病。这项研究将调查免疫系统的一种特定成分，称为补体蛋白，在精神分裂症患者的血液和大脑中的作用，以及它们如何影响患者的预后。这项研究将提高我们对精神分裂症的生物学因素的理解。