The control of group A streptococcal disease in endemic populations

流行人群中 A 族链球菌病的控制

• 批准号: nhmrc : 1052152
• 负责人: Prof Andrew Steer
• 金额: $ 27.69万
• 依托单位: The University of Melbourne
• 依托单位国家: 澳大利亚
• 项目类别: Career Development Fellowships
• 财政年份: 2013
• 资助国家: 澳大利亚
• 起止时间: 2013-01-01 至 2016-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/control-group-streptococcal-endemic-populations/112257
• 关键词: control; group; streptococcal; disease; endemic

Group A streptococcal diseases, including rheumatic heart disease, are major causes of illness globally, mostly in developing countries. This proposal is an investigation into how best to tackle control these diseases. It focuses on 1) a novel way to detect rheumatic heart disease in its earliest phases using ultrasound, 2) using a single drug once per year to stop streptococcal skin sores by controlling scabies infestation in whole communities and 3) developing a new vaccine that is applicable across all regions of the world.

A组链球菌疾病，包括风湿性心脏病，是全球主要疾病的主要原因，主要发生在发展中国家。这项建议是对如何最好地控制这些疾病的调查。它的重点是1）一种新的方法来检测风湿性心脏病在其最早阶段使用超声，2）使用单一的药物，每年一次，以阻止链球菌皮肤溃疡通过控制疥疮感染在整个社区和3）开发一种新的疫苗，适用于世界所有地区。